Sodium/Calcium Exchanger Monoclonal Antibody (6H2) | Invitrogen MA1-12751 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Sodium/Calcium Exchanger Monoclonal Antibody (6H2)

catalog :

MA1-12751

quantity :

10Miniblots

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H2

reactivity :

rabbit

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; rabbit; 1:5000	Lenčová Popelová O, Jirkovsky E, Mazurova Y, Lenco J, Adamcova M, Simunek T, et al. Molecular remodeling of left and right ventricular myocardium in chronic anthracycline cardiotoxicity and post-treatment follow up. PLoS ONE. 2014;9:e96055 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Sodium/Calcium Exchanger Monoclonal Antibody (6H2)

Catalog # :

MA1-12751

Quantity :

10Miniblots

Price :

US 425.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Rabbit

Applications :

Western Blot: 1:1000

Species :

Rabbit

Clone :

6H2

Isotype :

IgG2b

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: Three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two in the NaCKX family (NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling (Matsuoka et al., 1993). NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury (Hagihara et al., 2005; Bano et al., 2005; Choi, 2005).

Immunogen :

Fusion protein from the N-terminus of rabbit renal Na+/Ca2+ exchanger.

Format :

Lyophilized

Applications w/Dilutions :

Western Blot: 1:1000

Aliases :

Sodium/Calcium Exchanger 1