alpha-2b Adrenergic Receptor Monoclonal Antibody (5G10) | Invitrogen MA1-12721 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

alpha-2b Adrenergic Receptor Monoclonal Antibody (5G10)

catalog :

MA1-12721

quantity :

100 ug

price :

US 676.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G10

The same clone is also sold as:

OriGene: AM05339PU-N

reactivity :

mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

alpha-2b Adrenergic Receptor Monoclonal Antibody (5G10)

Catalog # :

MA1-12721

Quantity :

100 ug

Price :

US 676.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: Assay-dependent, Western Blot: 1-5 ug/mL

Species :

Mouse, Rat

Clone :

5G10

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.

Immunogen :

Synthetic peptide corresponding to the third intracellular loop of rat alpha 2b adrenergic receptor.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Western Blot: 1-5 ug/mL

Aliases :

[a]2B; ADA2B; Adra2b; Adra-2b; ADRA2B adrenergic, alpha-2B-, receptor; ADRA2L1; ADRA2RL1; ADRARL1; Adrenergic alpha2B- receptor class III; adrenergic receptor, alpha 2b; adrenergic, alpha-2B-, receptor; Adrenergic, alpha2B-, receptor class III; adrenoceptor alpha 2B; alpha-2 adrenergic receptor subtype C2; alpha-2-adrenergic receptor-like 1; alpha2B; alpha-2B adrenergic receptor; Alpha-2B adrenoceptor; alpha-2B adrenoreceptor; ALPHA2BAR; alpha-2BAR; alpha2-C2; FAME2; G-protein coupled receptor; subtype alpha2-C2