This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
APH1 Polyclonal Antibody
catalog :
PA5-13316
quantity :
400µL
price :
US 330.00
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
Product Type :
Antibody
Product Name :
APH1 Polyclonal Antibody
Catalog # :
PA5-13316
Quantity :
400µL
Price :
US 330.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
Species :
Human
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Immunogen :
KLH conjugated synthetic peptide between 77-109 amino acids from the N-terminal region of human APH1
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
Aliases :
Gamma-secretase subunit APH-1A; APH-1a; Aph-1alpha; Presenilin-stabilization factor; PSF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA