Polycystin 1 Polyclonal Antibody | Invitrogen OSP00005W product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Polycystin 1 Polyclonal Antibody

catalog :

OSP00005W

quantity :

100 µL

price :

US 429

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

Polycystin 1 Polyclonal Antibody

Catalog # :

OSP00005W

Quantity :

100 µL

Price :

US 429

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry: 1:300-1:2,000, Western Blot: 1:300-1:2,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Description :

Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.

Immunogen :

A synthetic peptide from human PKD1 conjugated to blue carrier protein was used as the antigen.

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry: 1:300-1:2,000, Western Blot: 1:300-1:2,000

Aliases :

Autosomal dominant polycystic kidney disease 1 protein; autosomal dominant polycystic kidney disease 1 protein homolog; mFLJ00285; PBP; PC1; Pc-1; PKD1; polycystic kidney disease 1 (autosomal dominant); polycystic kidney disease 1 homolog; polycystic kidney disease 1 homolog; polycystin-1; polycystic kidney disease-associated protein; polycystin 1; polycystin 1, transient receptor potential channel interacting; polycystin-1; transient receptor potential cation channel, subfamily P, member 1; TRPP1