Spectrin alpha-1 Monoclonal Antibody (17C7) | Invitrogen MA1-91738 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Spectrin alpha-1 Monoclonal Antibody (17C7)

catalog :

MA1-91738

quantity :

100µL

price :

US 489

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

17C7

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

Spectrin alpha-1 Monoclonal Antibody (17C7)

Catalog # :

MA1-91738

Quantity :

100µL

Price :

US 489

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1:100,000-1:1,000,000, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Frozen): 1:10-1:50, Western Blot: 1:100-1:1000

Species :

Human, Mouse, Rat

Clone :

17C7

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

Immunogen :

Recombinant alpha I spectrin (erythroid spectrin) SH3 domain.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:100,000-1:1,000,000, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Frozen): 1:10-1:50, Western Blot: 1:100-1:1000

Aliases :

EL2, HPP, HS3, SPH3, SPTA