TCF7 Monoclonal Antibody (7H3) | Invitrogen MA1-12485 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCF7 Monoclonal Antibody (7H3)

catalog :

MA1-12485

quantity :

100µg

price :

US 550.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7H3

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

TCF7 Monoclonal Antibody (7H3)

Catalog # :

MA1-12485

Quantity :

100µg

Price :

US 550.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Frozen): Assay Dependent, Western Blot: 0.5 - 2 µg/ml

Species :

Human

Clone :

7H3

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

TCF 1 (T cell factor 1) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with b catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 1 is closely related to LEF-1, both of which are transcription factors expressed in mice during T cell differentiation. They regulate the T cell receptor a enhancer in transfections assays. TCF 1 becomes transcriptionally active through interaction with b catenin. Also, numerous splice variants of TCF 1 have been identified. Overexpression of TCF-1-specific splice forms appears to correlate with the metastatic behavior of colorectal cancer cells and with overproduction of lymphoid tyrosine protein kinase p56(lck).

Immunogen :

Recombinant protein corresponding to aa 102-269 of human TCF1A splice variant protein fused to maltose binding protein (MBP)

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): Assay Dependent, Western Blot: 0.5 - 2 µg/ml

Aliases :

TCF7