Sorafenib (Nexavar) | Selleck Chemicals S1040 product information

product summary

company name :

Selleck Chemicals

product type :

chemical

product name :

Sorafenib (Nexavar)

catalog :

S1040

quantity :

10 g

price :

10,200.00 USD

more info or order :

Selleck Chemicals product webpage

citations: 2

Reference
Groenendijk F, Mellema W, van der Burg E, Schut E, Hauptmann M, Horlings H, et al. Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation. Int J Cancer. 2015;136:1434-44 pubmed publisher
Gelmedin V, Spiliotis M, Brehm K. Molecular characterisation of MEK1/2- and MKK3/6-like mitogen-activated protein kinase kinases (MAPKK) from the fox tapeworm Echinococcus multilocularis. Int J Parasitol. 2010;40:555-67 pubmed publisher

product information

Catalog Number :

S1040

Product Name :

Sorafenib (Nexavar)

Synonyms :

Bay 43-9006, Nexavar

Target :

Raf

CAS Number :

475207-59-1, 284461-73-0 (free base)

Formula :

C21H16ClF3N4O3.C7H8O3S

Quantity :

10 g

List Price :

10,200.00 USD

Description :

Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF. Find all the information about Sorafenib (Nexavar) for cell signaling research.

Product Type :

Chemical

more info or order :

Selleck Chemicals product webpage