This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Tom20 (FL-145)
catalog :
sc-11415
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, other
citations: 173
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2b
Miyahara K, Takano N, Yamada Y, Kazama H, Tokuhisa M, Hino H, et al. BRCA1 degradation in response to mitochondrial damage in breast cancer cells. Sci Rep. 2021;11:8735 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4b
Hung C, Lombardo P, Malik N, Brun S, Hellberg K, Van Nostrand J, et al. AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy. Sci Adv. 2021;7: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 5h
Cassidy L, Young A, Young C, Soilleux E, Fielder E, Weigand B, et al. Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk. Nat Commun. 2020;11:307 pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig 4b
Momcilovic M, Jones A, Bailey S, Waldmann C, Li R, Lee J, et al. In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2019;575:380-384 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Tang C, Han H, Liu Z, Liu Y, Yin L, Cai J, et al. Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury. Cell Death Dis. 2019;10:677 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig e10e
Bertholet A, Chouchani E, Kazak L, Angelin A, Fedorenko A, Long J, et al. H+ transport is an integral function of the mitochondrial ADP/ATP carrier. Nature. 2019;571:515-520 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4a
  • western blot; human; 1:1000; fig 4c
Cai M, Li S, Shuai Y, Li J, Tan J, Zeng Q. Genome-wide CRISPR-Cas9 viability screen reveals genes involved in TNF-α-induced apoptosis of human umbilical vein endothelial cells. J Cell Physiol. 2019;234:9184-9193 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3c
Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  • western blot; human; loading ...; fig 6d
Marrone L, Bus C, Schöndorf D, Fitzgerald J, Kübler M, Schmid B, et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018;13:e0192497 pubmed publisher
  • western blot; human; loading ...; fig 1b
  • western blot; mouse; loading ...; fig 1b
Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming F, Trung M, et al. Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Dev Cell. 2017;43:716-730.e7 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6e
Bitler B, Wu S, Park P, Hai Y, Aird K, Wang Y, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nat Cell Biol. 2017;19:962-973 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 7b
  • western blot; human; fig 4
Shiba Fukushima K, Ishikawa K, Inoshita T, Izawa N, Takanashi M, Sato S, et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Hum Mol Genet. 2017;26:3172-3185 pubmed publisher
  • western blot; rat; fig 3s1
  • immunocytochemistry; human; loading ...; fig 4s1
Monterisi S, Lobo M, Livie C, Castle J, Weinberger M, Baillie G, et al. PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling. elife. 2017;6: pubmed publisher
  • western blot; human; loading ...; fig 5a
Lu Y, Acoba M, Selvaraju K, Huang T, Nirujogi R, Sathe G, et al. Human adenine nucleotide translocases physically and functionally interact with respirasomes. Mol Biol Cell. 2017;28:1489-1506 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 1g
Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, et al. D-Glutamate is metabolized in the heart mitochondria. Sci Rep. 2017;7:43911 pubmed publisher
  • other; mouse; loading ...; fig 1e
  • western blot; mouse; loading ...; fig 1a
Li Z, Guo G, Wang H, Si X, Zhou G, Xiong Y, et al. TRPC5 channel modulates endothelial cells senescence. Eur J Pharmacol. 2017;802:27-35 pubmed publisher
  • flow cytometry; human; loading ...; fig 4f
  • immunocytochemistry; human; 1:250; loading ...; fig 1g
  • western blot; human; 1:500; loading ...; fig 1e,3g
Menges S, Minakaki G, Schaefer P, Meixner H, Prots I, Schlötzer Schrehardt U, et al. Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Sci Rep. 2017;7:42942 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 3a
Cooper H, Yang Y, Ylikallio E, Khairullin R, Woldegebriel R, Lin K, et al. ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. Hum Mol Genet. 2017;26:1432-1443 pubmed publisher
  • immunocytochemistry; human; fig 2a
  • western blot; human; fig 1b
Sugiura A, Mattie S, Prudent J, McBride H. Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes. Nature. 2017;542:251-254 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig s1c
  • western blot; mouse; 1:1000; loading ...; fig s1e
Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3c
  • western blot; human; loading ...; fig 2g
Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3d
Steffen J, Vashisht A, Wan J, Jen J, Claypool S, Wohlschlegel J, et al. Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. Mol Biol Cell. 2017;28:600-612 pubmed publisher
  • western blot; human; 1:250; loading ...; fig 2a
Caino M, Seo J, Aguinaldo A, Wait E, Bryant K, Kossenkov A, et al. A neuronal network of mitochondrial dynamics regulates metastasis. Nat Commun. 2016;7:13730 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 6C
  • western blot; mouse; 1:1000; fig 4A
Shen M, Jiang Y, Guan Z, Cao Y, Sun S, Liu H. FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy. Sci Rep. 2016;6:38090 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 3
Melo T, van Zomeren K, Ferrari M, Boddeke H, Copray J. Impairment of mitochondria dynamics by human A53T ?-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease. Exp Brain Res. 2017;235:731-742 pubmed publisher
  • immunocytochemistry; rat; 1:500; loading ...; fig s2
Shlevkov E, Kramer T, Schapansky J, LaVoie M, Schwarz T. Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proc Natl Acad Sci U S A. 2016;113:E6097-E6106 pubmed
  • western blot; human; loading ...; fig 2b
Cenini G, Rüb C, Bruderek M, Voos W. Amyloid ?-peptides interfere with mitochondrial preprotein import competence by a coaggregation process. Mol Biol Cell. 2016;27:3257-3272 pubmed
  • western blot; human; loading ...
Stroud D, Surgenor E, Formosa L, Reljic B, Frazier A, Dibley M, et al. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature. 2016;538:123-126 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7a
Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, et al. Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy. Cell Death Dis. 2016;7:e2330 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s4a
Tillberg P, Chen F, Piatkevich K, Zhao Y, Yu C, English B, et al. Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies. Nat Biotechnol. 2016;34:987-92 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3c
Moschoi R, Imbert V, Nebout M, Chiche J, Mary D, Prebet T, et al. Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy. Blood. 2016;128:253-64 pubmed publisher
  • western blot; rat; fig 5
Qvit N, Joshi A, Cunningham A, Ferreira J, Mochly Rosen D. Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death. J Biol Chem. 2016;291:13608-21 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1a
  • western blot; human; loading ...; fig 3d
Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed publisher
  • western blot; human; fig 2e
Lu Y, Galbraith L, Herndon J, Lü Y, Pras Raves M, Vervaart M, et al. Defining functional classes of Barth syndrome mutation in humans. Hum Mol Genet. 2016;25:1754-70 pubmed publisher
  • immunocytochemistry; mouse; 1:100; tbl 2
  • western blot; mouse; 1:2000; tbl 2
Carbognin E, Betto R, Soriano M, Smith A, Martello G. Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency. EMBO J. 2016;35:618-34 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s1e
Raman M, Sergeev M, Garnaas M, Lydeard J, Huttlin E, Goessling W, et al. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nat Cell Biol. 2015;17:1356-69 pubmed publisher
  • western blot; human; loading ...; fig 2b
Kim H, Nagano Y, Choi S, Park S, Kim H, Yao T, et al. HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation. Biochem Biophys Res Commun. 2015;464:1235-1240 pubmed publisher
  • western blot; human; 1:500; fig 4
Hämäläinen R, Ahlqvist K, Ellonen P, Lepistö M, Logan A, Otonkoski T, et al. mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling. Cell Rep. 2015;11:1614-24 pubmed publisher
  • western blot; human; fig 1a
Choi H, Choi Y, Kang H, Lim E, Park S, Lee H, et al. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Hum Mol Genet. 2015;24:1127-41 pubmed publisher
Um J, Shin D, Choi S, Nathan A, Kim Y, Lee D, et al. Selective induction of Rab9-dependent alternative mitophagy using a synthetic derivative of isoquinoline alleviates mitochondrial dysfunction and cognitive deficits in Alzheimer's disease models. Theranostics. 2024;14:56-74 pubmed publisher
Qiu J, Yue F, Zhu P, Chen J, Xu F, Zhang L, et al. FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes. Nat Commun. 2023;14:6344 pubmed publisher
Godtliebsen G, Larsen K, Bhujabal Z, Opstad I, Nager M, Punnakkal A, et al. High-resolution visualization and assessment of basal and OXPHOS-induced mitophagy in H9c2 cardiomyoblasts. Autophagy. 2023;:1-20 pubmed publisher
Mauri S, Bernardo G, Martinez A, Favaro M, Trevisan M, Cobraiville G, et al. USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons. Cells. 2023;12: pubmed publisher
Noguchi M, Kohno S, Pellattiero A, Machida Y, Shibata K, Shintani N, et al. Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line. Cell Death Dis. 2023;14:241 pubmed publisher
Arumugam S, Li B, Boodapati S, Nathanson M, Sun B, Ouyang X, et al. Mitochondrial DNA and the STING pathway are required for hepatic stellate cell activation. Hepatology. 2023;: pubmed publisher
Bachmann M, Rossa A, Varanita T, Fioretti B, Biasutto L, Milenkovic S, et al. Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo. Cell Death Dis. 2022;13:1055 pubmed publisher
Schwarz L, Sharma K, Dodi L, Rieder L, Fallier Becker P, Casadei N, et al. Miro1 R272Q disrupts mitochondrial calcium handling and neurotransmitter uptake in dopaminergic neurons. Front Mol Neurosci. 2022;15:966209 pubmed publisher
Soutar M, Melandri D, O Callaghan B, Annuario E, Monaghan A, Welsh N, et al. Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci. Brain. 2022;145:4349-4367 pubmed publisher
Tokuyama T, Uosaki H, Sugiura A, Nishitai G, Takeda K, Nagashima S, et al. Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience. 2022;25:104582 pubmed publisher
Giamogante F, Barazzuol L, Poggio E, Tromboni M, Brini M, Cali T. Stable Integration of Inducible SPLICS Reporters Enables Spatio-Temporal Analysis of Multiple Organelle Contact Sites upon Modulation of Cholesterol Traffic. Cells. 2022;11: pubmed publisher
Schwarz L, Fitzgerald J. Steady-State Levels of Miro1 Linked to Phosphorylation at Serine 156 and Mitochondrial Respiration in Dopaminergic Neurons. Cells. 2022;11: pubmed publisher
Ke P, Chang C, Hsiao Y. Baicalein Activates Parkin-Dependent Mitophagy through NDP52 and OPTN. Cells. 2022;11: pubmed publisher
Zhao Y, Hu D, Wang R, Sun X, Ropelewski P, Hubler Z, et al. ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models. Nat Commun. 2022;13:1121 pubmed publisher
Krantz S, Kim Y, Srivastava S, Leasure J, Toth P, Marsboom G, et al. Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation. J Biol Chem. 2021;297:101410 pubmed publisher
Uesugi R, Ishii S, Matsuura A, Itakura E. Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor. J Biol Chem. 2021;297:101279 pubmed publisher
Rossini M, García Casas P, Filadi R, Pizzo P. Loosening ER-Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain. Cells. 2021;10: pubmed publisher
Yan B, Li T, Coyaud E, Laurent E, St Germain J, Zhou Y, et al. C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy. Autophagy. 2021;:1-12 pubmed publisher
Larson Casey J, Gu L, Davis D, Cai G, Ding Q, He C, et al. Post-translational regulation of PGC-1α modulates fibrotic repair. FASEB J. 2021;35:e21675 pubmed publisher
Silwal P, Kim J, Jeon S, Lee J, Kim Y, Kim Y, et al. Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice. Commun Biol. 2021;4:548 pubmed publisher
Naia L, Pinho C, Dentoni G, Liu J, Leal N, Ferreira D, et al. Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling. BMC Biol. 2021;19:57 pubmed publisher
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher
Kojima W, Yamano K, Kosako H, Imai K, Kikuchi R, Tanaka K, et al. Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy. Autophagy. 2021;:1-26 pubmed publisher
Zanin M, Santos B, Antony P, Berenguer Escuder C, Larsen S, Hanss Z, et al. Mitochondria interaction networks show altered topological patterns in Parkinson's disease. NPJ Syst Biol Appl. 2020;6:38 pubmed publisher
Adachi Y, Kato T, Yamada T, Murata D, Arai K, Stahelin R, et al. Drp1 Tubulates the ER in a GTPase-Independent Manner. Mol Cell. 2020;80:621-632.e6 pubmed publisher
Ogasawara Y, Cheng J, Tatematsu T, Uchida M, Murase O, Yoshikawa S, et al. Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets. Nat Commun. 2020;11:4480 pubmed publisher
Wei Z, Greaney J, Loh W, Homer H. Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry. Nat Commun. 2020;11:3393 pubmed publisher
Elsherbini A, Kirov A, Dinkins M, Wang G, Qin H, Zhu Z, et al. Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity. Acta Neuropathol Commun. 2020;8:60 pubmed publisher
Abrisch R, Gumbin S, Wisniewski B, Lackner L, Voeltz G. Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology. J Cell Biol. 2020;219: pubmed publisher
Sánchez M, Vida Y, Perez Inestrosa E, Mascareñas J, Vazquez M, Sugiura A, et al. MitoBlue as a tool to analyze the mitochondria-lysosome communication. Sci Rep. 2020;10:3528 pubmed publisher
Kinzler M, Zielke S, Kardo S, Meyer N, Kogel D, van Wijk S, et al. STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts. Sci Rep. 2020;10:687 pubmed publisher
Lee D, Yoo J, Kim J, Kim S, Kim S, Lee H, et al. NEDD4L downregulates autophagy and cell growth by modulating ULK1 and a glutamine transporter. Cell Death Dis. 2020;11:38 pubmed publisher
Chumarina M, Russ K, Azevedo C, Heuer A, Pihl M, Collin A, et al. Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene. Acta Neuropathol Commun. 2019;7:208 pubmed publisher
Chao C, Gutiérrez Vázquez C, Rothhammer V, Mayo L, Wheeler M, Tjon E, et al. Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. Cell. 2019;179:1483-1498.e22 pubmed publisher
Lin Y, Li L, Nie W, Liu X, Adler A, Xiao C, et al. Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients. Nat Commun. 2019;10:5277 pubmed publisher
Busch J, Cipullo M, Atanassov I, Bratic A, Silva Ramos E, Schondorf T, et al. MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition. Cell Rep. 2019;29:1728-1738.e9 pubmed publisher
Van Haute L, Hendrick A, D Souza A, Powell C, Rebelo Guiomar P, Harbour M, et al. METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis. Nucleic Acids Res. 2019;47:10267-10281 pubmed publisher
Shcherbakov D, Teo Y, Boukari H, Cortés Sanchón A, Mantovani M, Osinnii I, et al. Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis. Commun Biol. 2019;2:381 pubmed publisher
Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
Sarraf S, Sideris D, Giagtzoglou N, Ni L, Kankel M, Sen A, et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep. 2019;29:225-235.e5 pubmed publisher
Maghool S, Cooray N, Stroud D, Aragao D, Ryan M, Maher M. Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6. Life Sci Alliance. 2019;2: pubmed publisher
Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
Paggio A, Checchetto V, Campo A, Menabò R, Di Marco G, Di Lisa F, et al. Identification of an ATP-sensitive potassium channel in mitochondria. Nature. 2019;572:609-613 pubmed publisher
Pajak A, Laine I, Clemente P, El Fissi N, Schober F, Maffezzini C, et al. Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo. PLoS Genet. 2019;15:e1008240 pubmed publisher
Van Hameren G, Campbell G, Deck M, Berthelot J, Gautier B, Quintana P, et al. In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathies. Acta Neuropathol Commun. 2019;7:13 pubmed publisher
Park J, Lee S, Jeong H, Kang M, Van Haute L, Minczuk M, et al. The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res. 2019;47:7078-7093 pubmed publisher
Livingston M, Wang J, Zhou J, Wu G, Ganley I, Hill J, et al. Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys. Autophagy. 2019;:1-21 pubmed publisher
Sica V, Bravo San Pedro J, Izzo V, Pol J, Pierredon S, Enot D, et al. Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate. Cell Rep. 2019;27:820-834.e9 pubmed publisher
Princely Abudu Y, Pankiv S, Mathai B, Håkon Lystad A, Bindesbøll C, Brenne H, et al. NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Dev Cell. 2019;49:509-525.e12 pubmed publisher
Wang B, Maxwell B, Joo J, Gwon Y, Messing J, Mishra A, et al. ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. Mol Cell. 2019;74:742-757.e8 pubmed publisher
Ho D, Lee H, Son I, Seol W. G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses. Anim Cells Syst (Seoul). 2019;23:106-111 pubmed publisher
D Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, Simula L, et al. Reversible induction of mitophagy by an optogenetic bimodular system. Nat Commun. 2019;10:1533 pubmed publisher
Farmer T, O Neill K, Naslavsky N, Luo X, Caplan S. Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane. Mol Biol Cell. 2019;30:1138-1146 pubmed publisher
Ader N, Hoffmann P, Ganeva I, Borgeaud A, Wang C, Youle R, et al. Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis. elife. 2019;8: pubmed publisher
Booty L, Gawel J, Cvetko F, Caldwell S, Hall A, Mulvey J, et al. Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo. Cell Chem Biol. 2019;26:449-461.e8 pubmed publisher
Ward J, Stoyas C, Switonski P, Ichou F, Fan W, Collins B, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019;26:1189-1202.e6 pubmed publisher
Padman B, Nguyen T, Uoselis L, Skulsuppaisarn M, Nguyen L, Lazarou M. LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy. Nat Commun. 2019;10:408 pubmed publisher
D Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, et al. The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. Mol Cell. 2019;73:775-787.e10 pubmed publisher
Chen Z, Lei C, Wang C, Li N, Srivastava M, Tang M, et al. Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics. Nat Commun. 2019;10:104 pubmed publisher
Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, et al. Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior. J Neurosci. 2019;39:1588-1604 pubmed publisher
Rawat P, Teodorof Diedrich C, Spector S. Human immunodeficiency virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia. Glia. 2019;67:802-824 pubmed publisher
Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed publisher
Bahat A, Goldman A, Zaltsman Y, Khan D, Halperin C, Amzallag E, et al. MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells. Nat Commun. 2018;9:5132 pubmed publisher
Chin H, Li M, Tan I, Ninnis R, Reljic B, Scicluna K, et al. VDAC2 enables BAX to mediate apoptosis and limit tumor development. Nat Commun. 2018;9:4976 pubmed publisher
Abuaita B, Schultz T, O Riordan M. Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus. Cell Host Microbe. 2018;24:625-636.e5 pubmed publisher
Kory N, Wyant G, Prakash G, Uit de Bos J, Bottanelli F, Pacold M, et al. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science. 2018;362: pubmed publisher
Lobo Jarne T, Nyvltová E, Pérez Pérez R, Timón Gómez A, Molinié T, Choi A, et al. Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics. Cell Rep. 2018;25:1786-1799.e4 pubmed publisher
Balboa D, Saarimäki Vire J, Borshagovski D, Survila M, Lindholm P, Galli E, et al. Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes. elife. 2018;7: pubmed publisher
Tischler J, Gruhn W, Reid J, Allgeyer E, Buettner F, Marr C, et al. Metabolic regulation of pluripotency and germ cell fate through α-ketoglutarate. EMBO J. 2019;38: pubmed publisher
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