This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Mouse 4-1BB/TNFRSF9/CD137 Antibody
catalog :
MAB9371
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
158321
reactivity :
human, mouse
citations: 3
Reference
Ho S, Xu Z, Thakur A, Fox M, Tan S, DiGiammarino E, et al. Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity. Mol Cancer Ther. 2020;19:1040-1051 pubmed publisher
Wells J, Cowled C, Farzaneh F, Noble A. Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. J Immunol. 2008;181:3422-31 pubmed
Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen S, et al. Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance. Arthritis Rheum. 2007;56:949-59 pubmed
product information
brand :
R&D Systems
master code :
MAB9371
SKU :
MAB9371-100
product name :
Mouse 4-1BB/TNFRSF9/CD137 Antibody
description :
The Mouse 4-1BB/TNFRSF9/CD137 Antibody from R&D Systems is a rat monoclonal antibody to 4-1BB/TNFRSF9/CD137. This antibody reacts with mouse. The Mouse 4-1BB/TNFRSF9/CD137 Antibody has been validated for the following applications: Agonist Activity.
target :
4-1BB/TNFRSF9/CD137
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
158321
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse 4-1BB, Val24-Leu187, Accession # P20334
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse 4-1BB in direct ELISAs and Western blots. In direct ELISAs, this antibody shows no cross-reactivity with recombinant mouse (rm) BAFF R, rmCD27, rmCD30, rmCD40, rmDR3, rmEDAR, rmFas, rmGITR, rmLT beta R, rmNGF R, rmOPG, rmRANK, rmTAJ, rmTNF RI, rmTNF RII, rh4-1BB, rhDR6, or rhHVEM.
gene symbol :
TNFRSF9
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB9371
accessionNumbers :
P20334
applications :
Agonist Activity
2020 USD :
339
2021 USD :
359 USD
alt names :
41BB, 4-1BB, 4-1BB ligand receptor, CD137, CD137 antigen, CD137MGC2172, CDw137, FLJ43501, ILA, ILAhomolog of mouse 4-1BB, induced by lymphocyte activation (ILA), interleukin-activated receptor, homolog of mouse Ly63, receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, tumor necrosis factor receptor superfamily member 9, tumor necrosis factor receptor superfamily, member 9
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.