Human/Mouse HIF-1 alpha/HIF1A APC-conjugated Antibody | R&D Systems IC1935A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse HIF-1 alpha/HIF1A APC-conjugated Antibody

catalog :

IC1935A

quantity :

100 Tests

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

241812

reactivity :

human, mouse

application :

flow cytometry

citations: 7

Reference
Aso K, Kono M, Kanda M, Kudo Y, Sakiyama K, Hisada R, et al. Itaconate ameliorates autoimmunity by modulating T cell imbalance via metabolic and epigenetic reprogramming. Nat Commun. 2023;14:984 pubmed publisher
Chryplewicz A, Scotton J, Tichet M, Zomer A, Shchors K, Joyce J, et al. Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity. Cancer Cell. 2022;40:1111-1127.e9 pubmed publisher
Ma S, Zhao Y, Lee W, Ong L, Lee P, Jiang Z, et al. Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy. Nat Commun. 2022;13:4118 pubmed publisher
Firmino N, Cederberg R, Lee C, Shi R, Wadsworth B, Franks S, et al. Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer. Oncoimmunology. 2021;10:1959978 pubmed publisher
Zhu B, Wu Y, Huang S, Zhang R, Son Y, Li C, et al. Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. Immunity. 2021;54:1200-1218.e9 pubmed publisher
Di Gioia M, Spreafico R, Springstead J, Mendelson M, Joehanes R, Levy D, et al. Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation. Nat Immunol. 2020;21:42-53 pubmed publisher
Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher

product information

brand :

R&D Systems

master code :

IC1935A

SKU :

IC1935A

product name :

Human/Mouse HIF-1 alpha/HIF1A APC-conjugated Antibody

unit size :

100 Tests

seo description :

The Human/Mouse HIF-1 alpha/HIF1A APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to HIF-1 alpha. This antibody reacts with human,mouse. The Human/Mouse HIF-1 alpha/HIF1A APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Intracellular Staining by Flow Cytometry.

target :

HIF-1 alpha/HIF1A

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

241812

conjugate :

Allophycocyanin

dilution :

Intracellular Staining by Flow Cytometry 10 uL/10^6 cells

host :

Mouse

immunogen :

E. coli -derived recombinant human HIF-1 alpha , Arg575-Asn826, Accession # Q16665.1

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Recognizes human and mouse HIF-1 alpha in direct ELISAs.

gene symbol :

HIF1A

top caption :

Detection of HIF-1a antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q16665.1

applications :

Intracellular Staining by Flow Cytometry,Flow Cytometry

USD :

469 USD

alt names :

AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF 1A, HIF1, HIF1 alpha, HIF-1 alpha, HIF-1a, HIF1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.