Human E-Selectin/CD62E Antibody | R&D Systems BBA26 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human E-Selectin/CD62E Antibody

catalog :

BBA26

quantity :

200 ug

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BBIG-E1

reactivity :

human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

citations: 6

Reference
Lam F, Da Q, Guillory B, Cruz M. Recombinant Human Vimentin Binds to P-Selectin and Blocks Neutrophil Capture and Rolling on Platelets and Endothelium. J Immunol. 2018;200:1718-1726 pubmed publisher
PachÃ³n PeÃ±a G, Donnelly C, Ruiz CaÃ±ada C, Katz A, FernÃ¡ndez Veledo S, Vendrell J, et al. A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells. Stem Cells. 2017;35:1080-1092 pubmed publisher
Poeter M, Brandherm I, Rossaint J, Rosso G, Shahin V, Skryabin B, et al. Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63. Nat Commun. 2014;5:3738 pubmed publisher
Pezeshkian B, Donnelly C, Tamburo K, Geddes T, Madlambayan G. Leukemia Mediated Endothelial Cell Activation Modulates Leukemia Cell Susceptibility to Chemotherapy through a Positive Feedback Loop Mechanism. PLoS ONE. 2013;8:e60823 pubmed publisher
Fitau J, Boulday G, Coulon F, Quillard T, Charreau B. The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways. J Biol Chem. 2006;281:20148-59 pubmed
Lawson C, Ainsworth M, Yacoub M, Rose M. Ligation of ICAM-1 on endothelial cells leads to expression of VCAM-1 via a nuclear factor-kappaB-independent mechanism. J Immunol. 1999;162:2990-6 pubmed

product information

brand :

R&D Systems

master code :

BBA26

SKU :

BBA26-200

product name :

Human E-Selectin/CD62E Antibody

description :

The Human E-Selectin/CD62E Antibody from R&D Systems is a mouse monoclonal antibody to E-Selectin/CD62E. This antibody reacts with human. The Human E-Selectin/CD62E Antibody has been validated for the following applications: Flow Cytometry, Immunoprecipitation, Adhesion Blockade, Immunofluorescence, Immunocytochemistry, CyTOF-ready.

target :

E-Selectin/CD62E

category :

Primary Antibodies

unit size :

200 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.

clonality :

Monoclonal

clone :

BBIG-E1

conjugate :

Unconjugated

host :

Mouse

immunogen :

Activated HUVEC human umbilical vein endothelial cells

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

This antibody binds to CHO cells transfected with human E-Selectin. It does not bind to COS cells transfected with human PECAM-1, P-Selectin, L-Selectin, VCAM-1, or ICAM-1.

gene symbol :

SELE

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

BBA26

applications :

Flow Cytometry, Immunoprecipitation, Adhesion Blockade, Immunofluorescence, Immunocytochemistry, CyTOF-ready

2020 USD :

289

2021 USD :

299 USD

alt names :

CD62 antigen-like family member E, CD62E, CD62E antigen, ELAM, ELAM1, ELAM-1, ELAM1E-selectin, endothelial adhesion molecule 1, Endothelial leukocyte adhesion molecule 1, ESEL, LECAM2, leukocyte endothelial cell adhesion molecule 2, Leukocyte-endothelial cell adhesion molecule 2, SELE, selectin E

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.