Glucosylceramidase / GBA Protein | R&D Systems 7410-GH-010 product information

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product summary

company name :

R&D Systems

product type :

protein

product name :

Glucosylceramidase / GBA Protein

catalog :

7410-GH-010

quantity :

10 ug

price :

339 USD

citations: 2

Reference
Choi S, Kim D, Kam T, Yun S, Kim S, Park H, et al. Lysosomal Enzyme Glucocerebrosidase Protects against AÎ²1-42 Oligomer-Induced Neurotoxicity. PLoS ONE. 2015;10:e0143854 pubmed publisher
Berger Z, Perkins S, Ambroise C, Oborski C, Calabrese M, Noell S, et al. Tool compounds robustly increase turnover of an artificial substrate by glucocerebrosidase in human brain lysates. PLoS ONE. 2015;10:e0119141 pubmed publisher

product information

SKU :

7410-GH-010

Description :

The Recombinant Human Glucosylceramidase / GBA Protein from R&D Systems is derived from CHO. The Recombinant Human Glucosylceramidase / GBA Protein has been validated for the following applications: Enzyme Activity.

Category :

Proteins and Enzymes

Size :

10 ug

Product Name :

Glucosylceramidase / GBA Protein

Alternate Names :

Acid beta-glucosidase, alglucerase, Beta-glucocerebrosidase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45, GBA, GBA1, GC, GCB, GLUC, glucosidase, beta, acid, glucosidase, beta; acid (includes glucosylceramidase), glucosylceramidase, imiglucerase, lysosomal glucocerebrosidase

Buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl, Glycerol and DTT.

Conjugate :

Unconjugated

Purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

Species Reactivity :

Human

Storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

Observed Molecular Weight :

58-75 kDa, reducing conditions

Theoretical Molecular Weight :

56 kDa

Gene Symbol :

GBA

Details of Functionality :

Measured by its ability to hydrolyze 4-methylumbelliferyl-beta-D-glucopyranoside. The specific activity is 180 pmol/min/╡g, as measured under the described conditions.

Endotoxin Note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

Target :

Glucosylceramidase / GBA

AccessionNumbers :

P04062

Applications :

Enzyme Activity

Source :

CHO-derived Recombinant Human Glucosylceramidase / GBA Protein, CF

USD :

339 USD