This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GSK3B
catalog :
22104-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 105
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; 1:500; loading ...; fig 2a
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, et al. Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway. EBioMedicine. 2019;48:386-404 pubmed publisher
  • western blot; human; 1:1000; fig 5
Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, et al. TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis. Sci Rep. 2016;6:24859 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Pan Y, Deng Y, Xie S, Wang Z, Wang Y, Ren J, et al. Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3? and ?-catenin. Chin Med J (Engl). 2016;129:838-45 pubmed publisher
Kang D, Zuo W, Wu Q, Zhu Q, Liu P. Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer. Biomed Res Int. 2020;2020:1358674 pubmed publisher
Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, et al. Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways. Biomed Pharmacother. 2020;130:110522 pubmed publisher
Wang S, Chao D, Wei W, Nan G, Li J, Liu F, et al. CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma. J Exp Clin Cancer Res. 2020;39:145 pubmed publisher
Song Y, Yuan H, Wang J, Wu Y, Xiao Y, Mao S. KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway. Cancer Manag Res. 2020;12:3981-3993 pubmed publisher
Sun X, Peng X, Cao Y, Zhou Y, Sun Y. ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling. Nat Commun. 2020;11:2984 pubmed publisher
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, et al. BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway. Int Immunopharmacol. 2020;85:106625 pubmed publisher
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, et al. Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis. Biomed Res Int. 2020;2020:4910601 pubmed publisher
Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, et al. Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer. Cell Biol Toxicol. 2020;: pubmed publisher
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, et al. Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia. IUBMB Life. 2020;72:1659-1679 pubmed publisher
Song J, Liu L, Lv L, Hu S, Tariq A, Wang W, et al. Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells. Cell Biol Int. 2020;44:1491-1502 pubmed publisher
Yu Y, Cai L, Wang X, Cheng S, Zhang D, Jian W, et al. BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma. Cancer Sci. 2020;111:1555-1566 pubmed publisher
Cooper L, Hanson A, Kavanagh J, Waddell D. Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy. Cell Signal. 2020;70:109576 pubmed publisher
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, et al. Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity. Cell Rep. 2020;30:1835-1847.e9 pubmed publisher
Zhang R, Liu J, Zhang W, Hua L, Qian L, Zhou S. EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway. Cancer Cell Int. 2020;20:20 pubmed publisher
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, et al. FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors. Aging (Albany NY). 2020;12:53-69 pubmed publisher
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, et al. Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma. BMC Cancer. 2020;20:31 pubmed publisher
Guo L, Yang T. Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway. Cancer Manag Res. 2019;11:10499-10508 pubmed publisher
Zhu M, Yu X, Zheng Z, Huang J, Yang X, Shi H. Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway. Phytother Res. 2019;: pubmed publisher
Li K, Pan W, Ma Y, Xu X, Gao Y, He Y, et al. BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer. Breast Cancer. 2019;: pubmed publisher
Gang W, Tanjun W, Yong H, Jiajun Q, Yi Z, Hao H. Inhibition of miR-9 decreases osteosarcoma cell proliferation. Bosn J Basic Med Sci. 2019;: pubmed publisher
Wei X, Jia Y, Lou H, Ma J, Huang Q, Meng Y, et al. Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway. Oncol Rep. 2019;42:2768-2776 pubmed publisher
Lu Z, Chang L, Zhou H, Liu X, Li Y, Mi T, et al. Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro. Front Pharmacol. 2019;10:937 pubmed publisher
Yang S, Chen Y, Duan Y, Ma C, Liu L, Li Q, et al. Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice. Biomed Pharmacother. 2019;118:109389 pubmed publisher
Xu D, Hou K, Li F, Chen S, Fang W, Li Y. XQ-1H alleviates cerebral ischemia in mice through inhibition of apoptosis and promotion of neurogenesis in a Wnt/β-catenin signaling dependent way. Life Sci. 2019;235:116844 pubmed publisher
Yang R, Zhou Y, Song W, Yin Z, He A, Ming Z. Pharmacological actions of neferine in the modulation of human platelet function. Eur J Pharmacol. 2019;:172626 pubmed publisher
Wang J, Yang J, Cheng X, Yin F, Zhao Y, Zhu Y, et al. Influence of Calcium Supplementation against Fluoride-Mediated Osteoblast Impairment in Vitro: Involvement of the Canonical Wnt/β-Catenin Signaling Pathway. J Agric Food Chem. 2019;67:10285-10295 pubmed publisher
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, et al. miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway. J Exp Clin Cancer Res. 2019;38:358 pubmed publisher
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, et al. Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism. Mol Biol Rep. 2019;: pubmed publisher
Chen W, He B, Tong W, Zeng J, Zheng P. Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity. Front Cell Neurosci. 2019;13:298 pubmed publisher
Yang K, Chen Y, Zhou J, Ma L, Shan Y, Cheng X, et al. Ursolic Acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in NSCLCs harboring EGFR T790M. Br J Pharmacol. 2019;: pubmed publisher
Liu X, Rong Z, Shou C. Mycoplasma hyorhinis infection promotes gastric cancer cell motility via β-catenin signaling. Cancer Med. 2019;8:5301-5312 pubmed publisher
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, et al. Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma. Oncol Lett. 2019;18:609-616 pubmed publisher
Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, et al. Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells. Toxicology. 2019;: pubmed publisher
Yang R, Jia Q, Ma S, Wang Y, Mehmood S, Chen Y. Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway. Int J Mol Med. 2019;44:549-558 pubmed publisher
Wang X, Luo C, Mao X, Li X, Yin J, Zhang W, et al. Metformin reverses the schizophrenia-like behaviors induced by MK-801 in rats. Brain Res. 2019;: pubmed publisher
Liu Y, Wang H, Liu N, Du J, Lan X, Qi X, et al. Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway. Life Sci. 2019;: pubmed publisher
Liu B, Ma H, Liu Q, Xiao Y, Pan S, Zhou H, et al. MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia. J Exp Clin Cancer Res. 2019;38:200 pubmed publisher
Liu D, Zhang Y, Hu H, Zhang P, Cui W. Downregulation of microRNA‑199a‑5p attenuates hypoxia/reoxygenation‑induced cytotoxicity in cardiomyocytes by targeting the HIF‑1α‑GSK3β‑mPTP axis. Mol Med Rep. 2019;19:5335-5344 pubmed publisher
Shao J, Han B, Cao P, Zhang B, Liu M, Li D, et al. HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression. Biochim Biophys Acta Gene Regul Mech. 2019;: pubmed publisher
Li S, Huang Q, Zhang L, Qiao X, Zhang Y, Tang F, et al. Effect of CAPE-pNO2 against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice. Eur J Pharmacol. 2019;853:1-10 pubmed publisher
Wang Q, Lv Q, Bian H, Yang L, Guo K, Ye S, et al. A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer. Cancer Med. 2019;8:2360-2371 pubmed publisher
Zhu L, Wu G, Yang X, Jia X, Li J, Bai X, et al. Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells. Sci Rep. 2019;9:3020 pubmed publisher
Peng W, Tong C, Li L, Huang C, Ran Y, Chen X, et al. Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia. FASEB J. 2019;33:6327-6338 pubmed publisher
Wang T, Sun C, Zhong H, Gong Y, Cui Z, Xie J, et al. N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide promotes bone formation via the canonical Wnt/β-catenin signaling pathway. Phytother Res. 2019;33:1074-1083 pubmed publisher
Li W, Wang D, Sun X, Zhang Y, Wang L, Suo J. ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways. Int J Mol Med. 2019;43:914-926 pubmed publisher
Chen C, Zhou F, Zeng L, Jiang Z, Hu Z. Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway. J Cell Physiol. 2019;234:5304-5318 pubmed publisher
Xu L, Xing Q, Huang T, Zhou J, Liu T, Cui Y, et al. HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway. Front Cell Neurosci. 2018;12:498 pubmed publisher
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, et al. High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway. Cell Physiol Biochem. 2018;50:2046-2059 pubmed publisher
Yang Y, Sun Y, Xu J, Bao K, Luo M, Liu X, et al. Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway. Mediators Inflamm. 2018;2018:3685948 pubmed publisher
Yu B, Wu K, Wang X, Zhang J, Wang L, Jiang Y, et al. Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7. Cell Death Dis. 2018;9:1082 pubmed publisher
Liu Z, Li R, Jiang C, Zhao S, Li W, Tang X. The neuroprotective effect of lithium chloride on cognitive impairment through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats. Eur J Pharmacol. 2018;840:50-59 pubmed publisher
Yao R, Sun X, Xie Y, Liu L, Han D, Yao Y, et al. Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway. Am J Transl Res. 2018;10:2610-2618 pubmed
Chen Y, Li Y, Wang X, Meng Y, Zhang Q, Zhu J, et al. Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway. Phytother Res. 2018;32:2447-2455 pubmed publisher
Zheng T, Yang X, Li W, Wang Q, Chen L, Wu D, et al. Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway. Oxid Med Cell Longev. 2018;2018:8597897 pubmed publisher
Li K, Ma Y, Zhang Z, Tian Y, Xu X, He Y, et al. Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3?/?-catenin signaling pathway in breast cancer. Cancer Med. 2018;7:3875-3888 pubmed publisher
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, et al. Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties. J Hematol Oncol. 2018;11:82 pubmed publisher
Ma L, Gao M, Wu L, Zhao X, Mao H, Xing C. The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells. Cell Biol Int. 2018;42:1270-1274 pubmed publisher
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, et al. P21-activated kinase 7 (PAK7) interacts with and activates Wnt/?-catenin signaling pathway in breast cancer. J Cancer. 2018;9:1821-1835 pubmed publisher
Song M, Ruan J, Zhang R, Deng J, Ma Z, Ma S. Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis. Acta Pharmacol Sin. 2018;39:1559-1570 pubmed publisher
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, et al. Wnt/?-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention. Toxicol Lett. 2018;291:70-76 pubmed publisher
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, et al. Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model. Chin Med. 2018;13:17 pubmed publisher
Zhang Q, Li X, Chen Y, Chen J, Zhu J, Meng Y, et al. Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells. Cancer Chemother Pharmacol. 2018;81:969-977 pubmed publisher
Xu W, He L, Li Y, Tan Y, Zhang F, Xu H. Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/β-catenin signaling in gastric cancer cells. Biosci Biotechnol Biochem. 2018;82:456-465 pubmed publisher
Xing F, Yi W, Miao F, Su M, Lei T. Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice. Int J Mol Med. 2018;41:2079-2085 pubmed publisher
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, et al. Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway. J Cell Biochem. 2018;119:4134-4141 pubmed publisher
Duan X, Meng Q, Wang C, Liu Z, Sun H, Huo X, et al. Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice. J Gastroenterol Hepatol. 2018;33:533-542 pubmed publisher
Chengye W, Yu T, Ping S, Deguang S, Keyun W, Yan W, et al. Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells. Oncotarget. 2017;8:104247-104257 pubmed publisher
Chen S, Wang L, Yao X, Chen H, Xu C, Tong L, et al. miR-195-5p is critical in REG?-mediated regulation of wnt/?-catenin pathway in renal cell carcinoma. Oncotarget. 2017;8:63986-64000 pubmed publisher
Yang H, Yu M, Jin H, Yao J, Lu Z, Yabasin I, et al. Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating ?1, 6-Fucosylation via Wnt/?-Catenin Signaling Pathway. Front Physiol. 2017;8:510 pubmed publisher
Song N, Cao C, Tang Y, Bi L, Jiang Y, Zhou Y, et al. The ubiquitin ligase SCFFBXW7? promotes GATA3 degradation. J Cell Physiol. 2017;: pubmed publisher
Sun H, Xu D, Sun Y, Xue T, Zhang C, Zhang Z, et al. CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/?-catenin pathway. Biochem Biophys Res Commun. 2017;490:629-635 pubmed publisher
Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, et al. REG? accelerates melanoma formation by regulating Wnt/?-catenin signalling pathway. Exp Dermatol. 2017;26:1118-1124 pubmed publisher
Chen Y, Wang X, Zhang Q, Zhu J, Li Y, Xie C, et al. (-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway. Nutrients. 2017;9: pubmed publisher
Song Z, Yang W, Zhou X, Yang L, Zhao D. Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling. Neuropharmacology. 2017;123:332-348 pubmed publisher
Song Z, Shah S, Yang W, Dong H, Yang L, Zhou X, et al. Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-?-Catenin Signaling in Prion Diseases Models. Front Mol Neurosci. 2017;10:128 pubmed publisher
Yuan X, Huang H, Huang Y, Wang J, Yan J, Ding L, et al. Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes. Exp Biol Med (Maywood). 2017;242:930-938 pubmed publisher
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, et al. miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells. J Nutr Biochem. 2017;44:80-91 pubmed publisher
Yang X, Tang S, Dai C, Li D, Zhang S, Deng S, et al. Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/?-catenin signaling pathway. Food Chem Toxicol. 2017;105:161-176 pubmed publisher
Li W, Yang X, Zheng T, Xing S, Wu Y, Bian F, et al. TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance. Sci Rep. 2017;7:44659 pubmed publisher
Zhu J, Yang X, Chen Y, Jiang Y, Wang S, Li Y, et al. Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/?-catenin and Sonic Hedgehog Pathways. Phytother Res. 2017;31:680-688 pubmed publisher
Xiang D, Cheng Z, Liu H, Wang X, Han T, Sun W, et al. Shp2 promotes liver cancer stem cell expansion by augmenting ?-catenin signaling and predicts chemotherapeutic response of patients. Hepatology. 2017;65:1566-1580 pubmed publisher
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, et al. Wnt/?-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells. Biochem Biophys Res Commun. 2017;482:15-21 pubmed publisher
Zhang Y, Yang X, Jin G, Yang X, Zhang Y. Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease. Int J Biol Macromol. 2016;92:935-941 pubmed publisher
Zhang J, Wen X, Ren X, Li Y, Tang X, Wang Y, et al. YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway. J Exp Clin Cancer Res. 2016;35:109 pubmed publisher
Zhao Z, Zhang X, Wen L, Yi S, Hu J, Ruan J, et al. Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation. Eur J Pharmacol. 2016;789:46-59 pubmed publisher
Wang J, Wan X, Gao Y, Zhong M, Sha L, Liu B, et al. Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells. Oncol Rep. 2016;36:441-7 pubmed publisher
Liu Y, Dong M, Yang Z, Pan S. Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K/Akt signaling pathway. Int J Biol Macromol. 2016;89:484-8 pubmed publisher
Chen S, Sun K, Feng M, Sang X, Liu B, Zhao Y. Role of glycogen synthase kinase-3? inhibitor AZD1080 in ovarian cancer. Drug Des Devel Ther. 2016;10:1225-32 pubmed publisher
Chen S, Sun K, Liu B, Zong Z, Zhao Y. The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker. Oncotarget. 2016;7:27538-51 pubmed publisher
Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, et al. REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling. Oncotarget. 2016;7:12035-52 pubmed publisher
Du J, Niu X, Wang Y, Kong L, Wang R, Zhang Y, et al. MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a. Sci Rep. 2015;5:16163 pubmed publisher
Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, et al. Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice. Neuropsychopharmacology. 2016;41:1340-9 pubmed publisher
Wang X, Wang M, Li H, Lan X, Liu L, Li J, et al. Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor. Mol Cell Endocrinol. 2015;416:57-69 pubmed publisher
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, et al. Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways. Sci Rep. 2015;5:11614 pubmed publisher
Liu Y, Zhou R, Yuan X, Han N, Zhou S, Xu H, et al. DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling. Oncotarget. 2015;6:8621-34 pubmed
Li L, Dang Y, Zhang J, Yan W, Zhai W, Chen H, et al. REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway. Nat Commun. 2015;6:6875 pubmed publisher
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, et al. Potent effects of dioscin against liver fibrosis. Sci Rep. 2015;5:9713 pubmed publisher
Zhang Y, Zhang X, Huang J, Dong Q. Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines. Med Oncol. 2015;32:157 pubmed publisher
Zheng T, Yang X, Wu D, Xing S, Bian F, Li W, et al. Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway. Br J Pharmacol. 2015;172:3284-301 pubmed publisher
Hao Y, Su Z, Lv X, Li P, Gao P, Wang C, et al. RNA-binding motif protein 5 negatively regulates the activity of Wnt/β-catenin signaling in cigarette smoke-induced alveolar epithelial injury. Oncol Rep. 2015;33:2438-44 pubmed publisher
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, et al. Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo. Int J Oncol. 2015;46:360-8 pubmed publisher
Chen X, Xie X, Zhao Q, Wang F, Bai Y, Yin J, et al. Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells. Mol Med Rep. 2015;11:105-12 pubmed publisher
product information
CatalogNo :
22104-1-AP
AntigenName :
GSK3B
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
glycogen synthase kinase 3 beta
Immunogen :
Fusion Protein
Species :
hamster, human, mouse, pig, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
GSK 3 beta, GSK3 beta, GSK3A B, GSK3B, GSK-3B, GSK3B 216P, gsk3beta, GSK-3beta, GSK3β
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000251
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Metabolism;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:1000 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.