product summary
request information :
company name :
Proteintech Group
product type :
product name :
catalog :
quantity :
150 ul
price :
clonality :
host :
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
publications citing this reagent :
total: 15
  1. Yan J, Zhang Y, Liao J, Ke K, Chang Y, Li P, et al. MiR-497 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting VEGFA and AEG-1. Oncotarget. 2015;6:29527-42 pubmed publisher
  2. Zhu G, Yu C, She L, Tan H, Li G, Ren S, et al. Metadherin regulation of vascular endothelial growth factor expression is dependent upon the PI3K/Akt pathway in squamous cell carcinoma of the head and neck. Medicine (Baltimore). 2015;94:e502 pubmed publisher
  3. Yang G, Zhang L, Lin S, Li L, Liu M, Chen H, et al. AEG-1 is associated with tumor progression in nonmuscle-invasive bladder cancer. Med Oncol. 2014;31:986 pubmed publisher
  4. Yu C, Liu Y, Tan H, Li G, Su Z, Ren S, et al. Metadherin regulates metastasis of squamous cell carcinoma of the head and neck via AKT signalling pathway-mediated epithelial-mesenchymal transition. Cancer Lett. 2014;343:258-67 pubmed publisher
  5. Long M, Dong K, Gao P, Wang X, Liu L, Yang S, et al. Overexpression of astrocyte-elevated gene-1 is associated with cervical carcinoma progression and angiogenesis. Oncol Rep. 2013;30:1414-22 pubmed publisher
  6. Zhang J, Zhang Y, Liu S, Zhang Q, Wang Y, Tong L, et al. Metadherin confers chemoresistance of cervical cancer cells by inducing autophagy and activating ERK/NF-κB pathway. Tumour Biol. 2013;34:2433-40 pubmed publisher
  7. Long M, Hao M, Dong K, Shen J, Wang X, Lin F, et al. AEG-1 overexpression is essential for maintenance of malignant state in human AML cells via up-regulation of Akt1 mediated by AURKA activation. Cell Signal. 2013;25:1438-46 pubmed publisher
  8. Liu Y, Su Z, Li G, Yu C, Ren S, Huang D, et al. Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma. Int J Cancer. 2013;133:671-9 pubmed publisher
  9. Zhou J, Li J, Wang Z, Yin C, Zhang W. Metadherin is a novel prognostic marker for bladder cancer progression and overall patient survival. Asia Pac J Clin Oncol. 2012;8:e42-8 pubmed publisher
  10. Gong Z, Liu W, You N, Wang T, Wang X, Lu P, et al. Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma. Oncol Rep. 2012;27:2073-9 pubmed publisher
more info or order :
product information
Catalog Number :
Item Name :
Quantity / Package Size :
150 ul
FullName :
Antigen :
Recombinant Protein
Species Reactivity :
human, mouse, rat
Host Species :
Conjugate :
Antigen Species :
Applications :
Type :
Isotype :
Antigen Synonyms :
3D3, 3D3/LYRIC, AEG 1, AEG1, LYRIC, LYRIC/3D3, metadherin, Metastasis adhesion protein, MTDH, Protein LYRIC
Primary or Secondary? :
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
Category :
Autophagy;Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;
Price :
Form/Purification :
Antigen affinity purification
Description2 :
The AEG-1/MTDH-Specific antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AEG-1/MTDH-Specific. This antibody recognizes human,mouse,rat antigen. The AEG-1/MTDH-Specific antibody has been validated for the following applications: ELISA, WB, IHC, IF, IP analysis.
20625905, 21105004, 21259255, 21495225, 21750868, 22056881, 22470125, 22898150, 23364922, 23499911, 23595222, 23835593, 24099913, 24829140, 25674742, 26336827
IsSellable :
Feature :
AppTiter :
WB 1:1000 ; IHC 1:100 ; IF 1:50 ; IP 1:1000 ;
publications citing this reagent :
  1. He X, Chang Y, Meng F, Wang M, Xie Q, Tang F, et al. MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo. Oncogene. 2012;31:3357-69 pubmed publisher
  2. Sun W, Fan Y, Xi H, Lu X, Ye C, Zhang J. Astrocyte elevated gene-1 overexpression in human primary gallbladder carcinomas: an unfavorable and independent prognostic factor. Oncol Rep. 2011;26:1133-42 pubmed publisher
  3. Song H, Li C, Lu R, Zhang Y, Geng J. Expression of astrocyte elevated gene-1: a novel marker of the pathogenesis, progression, and poor prognosis for endometrial cancer. Int J Gynecol Cancer. 2010;20:1188-96 pubmed
  4. Li C, Li R, Song H, Wang D, Feng T, Yu X, et al. Significance of AEG-1 expression in correlation with VEGF, microvessel density and clinicopathological characteristics in triple-negative breast cancer. J Surg Oncol. 2011;103:184-92 pubmed publisher
  5. Song H, Li C, Li R, Geng J. Prognostic significance of AEG-1 expression in colorectal carcinoma. Int J Colorectal Dis. 2010;25:1201-9 pubmed publisher
more info or order :
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.