This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MLXIP
catalog :
13614-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 11
Reference
Chow H, Shi M, Cheng A, Gao Y, Chen G, Song X, et al. Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence. Nat Neurosci. 2019;22:1806-1819 pubmed publisher
Ahn B, Wan S, Jaiswal N, Vega R, Ayer D, Titchenell P, et al. MondoA drives muscle lipid accumulation and insulin resistance. JCI Insight. 2019;5: pubmed publisher
Wilde B, Ye Z, Lim T, Ayer D. Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production. elife. 2019;8: pubmed publisher
Wang C, Xu Y, Wang X, Guo C, Wang T, Wang Z. Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis. Antioxid Redox Signal. 2019;30:1411-1431 pubmed publisher
Zhang B, Lyu J, Liu Y, Wu C, Yang E, Pardeshi L, et al. BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition. Oncogene. 2018;37:6341-6356 pubmed publisher
Ye Z, Ayer D. Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation. Mol Cell Biol. 2018;38: pubmed publisher
Richards P, Rachdi L, Oshima M, Marchetti P, Bugliani M, Armanet M, et al. MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells. Diabetes. 2018;67:461-472 pubmed publisher
Sanchez E, Carroll P, Thalhofer A, Lagunoff M. Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival. PLoS Pathog. 2015;11:e1005052 pubmed publisher
Shen L, O Shea J, Kaadige M, Cunha S, Wilde B, Cohen A, et al. Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP. Proc Natl Acad Sci U S A. 2015;112:5425-30 pubmed publisher
Carroll P, Diolaiti D, McFerrin L, Gu H, Djukovic D, Du J, et al. Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis. Cancer Cell. 2015;27:271-85 pubmed publisher
Kaadige M, Yang J, Wilde B, Ayer D. MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction. Mol Cell Biol. 2015;35:101-10 pubmed publisher
product information
CatalogNo :
13614-1-AP
AntigenName :
MLXIP
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
MLX interacting protein
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
bHLHe36, KIAA0867, MIR, MLX interacting protein, MLXIP, MONDOA
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC039704
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:100 ; IP 1:300 ; WB 1:300 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.