This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
VDAC1/2
catalog :
10866-1-AP
quantity :
150UL
price :
99 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 46
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1g
Malty R, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, et al. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017;5:564-577.e12 pubmed publisher
Ji Y, Zhang J, Lu Y, Yi Q, Chen M, Xie S, et al. Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy. J Biol Chem. 2020;: pubmed publisher
Wang N, Liu H, Liu G, Li M, He X, Yin C, et al. Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis. Redox Biol. 2020;32:101495 pubmed publisher
Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, et al. Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165575 pubmed publisher
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, et al. Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum. Cells. 2019;9: pubmed publisher
Nie J, Ta N, Liu L, Shi G, Kang T, Zheng Z. Activation of CaMKII via ER-stress mediates coxsackievirus B3-induced cardiomyocyte apoptosis. Cell Biol Int. 2019;: pubmed publisher
Violitzi F, Perivolidi V, Thireou T, Grivas I, Haralambous S, Samiotaki M, et al. Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice. J Proteome Res. 2019;18:3896-3912 pubmed publisher
Wang Z, Yuan C, Huang Y, Liu Z, Yu X, Lv C, et al. Decreased expression of apoptosis-inducing factor in renal cell carcinoma is associated with poor prognosis and reduced postoperative survival. Oncol Lett. 2019;18:2805-2812 pubmed publisher
Chai N, Zhang H, Li L, Yu X, Liu Y, Lin Y, et al. Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation. Oxid Med Cell Longev. 2019;2019:5406468 pubmed publisher
Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, et al. Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity. Biochem Biophys Res Commun. 2019;: pubmed publisher
Si L, Liu W, Hayashi T, Ji Y, Fu J, Nie Y, et al. Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment. Arch Biochem Biophys. 2019;671:42-51 pubmed publisher
Zhao X, Wu Y, Li J, Li D, Jin Y, Zhu P, et al. JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation. Toxicology. 2019;423:42-53 pubmed publisher
Ye J, Ma J, Liu C, Huang J, Wang L, Zhong X. A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage. Biochem Pharmacol. 2019;166:93-107 pubmed publisher
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, et al. A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer. Cell Cycle. 2019;18:1019-1032 pubmed publisher
Liu C, Huang S, Wang X, Wen M, Zheng J, Wang W, et al. The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination. J Immunol. 2019;202:2957-2970 pubmed publisher
Chen D, Zhang Z, Chen C, Yao S, Yang Q, Li F, et al. Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism. Nucleic Acids Res. 2019;47:5341-5355 pubmed publisher
Zhao Y, Wang Z, Feng D, Zhao H, Lin M, Hu Y, et al. p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species. Theranostics. 2019;9:1510-1522 pubmed publisher
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, et al. Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway. EBioMedicine. 2019;39:239-254 pubmed publisher
Ji Y, Zhang J, Yu J, Wang Y, Lu Y, Liang M, et al. Contribution of mitochondrial ND1 3394T>C mutation to the phenotypic manifestation of Leber's hereditary optic neuropathy. Hum Mol Genet. 2018;: pubmed publisher
Micheva K, Chang E, Nana A, Seeley W, Ting J, Cobbs C, et al. Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex. Eneuro. 2018;5: pubmed publisher
Bastian C, Politano S, Day J, McCray A, Brunet S, Baltan S. Mitochondrial dynamics and preconditioning in white matter. Cond Med. 2018;1:64-72 pubmed
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, et al. DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling. Cell Res. 2018;28:833-854 pubmed publisher
Cai J, Jiang Y, Zhang M, Zhao H, Li H, Li K, et al. Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury. J Physiol Biochem. 2018;74:335-343 pubmed publisher
Asano K, Suzuki T, Saito A, Wei F, Ikeuchi Y, Numata T, et al. Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease. Nucleic Acids Res. 2018;46:1565-1583 pubmed publisher
Sun Y, Tian Z, Liu N, Zhang L, Gao Z, Sun X, et al. Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice. J Mol Med (Berl). 2018;96:281-299 pubmed publisher
Li S, Wang T, Zhai L, Ge K, Zhao J, Cong W, et al. Picroside II Exerts a Neuroprotective Effect by Inhibiting mPTP Permeability and EndoG Release after Cerebral Ischemia/Reperfusion Injury in Rats. J Mol Neurosci. 2018;64:144-155 pubmed publisher
Kong X, Wei J, Wang D, Zhu X, Zhou Y, Wang S, et al. Upregulation of Spinal Voltage-Dependent Anion Channel 1 Contributes to Bone Cancer Pain Hypersensitivity in Rats. Neurosci Bull. 2017;33:711-721 pubmed publisher
Wang G, Lü M, Yao Y, Wang J, Li J. Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway. Eur J Pharmacol. 2017;814:207-215 pubmed publisher
Li J, Chen K, Wang F, Dai W, Li S, Feng J, et al. Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice. Oncotarget. 2017;8:45965-45980 pubmed publisher
Yang X, Tang S, Dai C, Li D, Zhang S, Deng S, et al. Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/?-catenin signaling pathway. Food Chem Toxicol. 2017;105:161-176 pubmed publisher
Feng D, Yao J, Wang G, Li Z, Zu G, Li Y, et al. Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats. Clin Sci (Lond). 2017;131:759-773 pubmed publisher
Li J, Li S, Wang X, Wang H. Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways. Can J Physiol Pharmacol. 2017;95:787-794 pubmed publisher
Li Q, Tang Y, Qin J, Yi L, Yang Y, Wang J, et al. Subcellular localization of DJ-1 in human HL-60 leukemia cells in response to diallyl disulfide treatment. Mol Med Rep. 2016;14:4666-4672 pubmed publisher
Grønborg S, Darin N, Miranda M, Damgaard B, Cayuela J, Oldfors A, et al. Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling. JIMD Rep. 2017;33:69-77 pubmed publisher
Di Nottia M, Masciullo M, Verrigni D, Petrillo S, Modoni A, Rizzo V, et al. DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7. Clin Genet. 2017;92:18-25 pubmed publisher
Zhang T, Zhang Q, Guo J, Yuan H, Peng H, Cui L, et al. Non-cytotoxic concentrations of acetaminophen induced mitochondrial biogenesis and antioxidant response in HepG2 cells. Environ Toxicol Pharmacol. 2016;46:71-79 pubmed publisher
Zhang C, Ding W, Liu Y, Hu Z, Zhu D, Wang X, et al. Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma. Oncotarget. 2016;7:52317-52328 pubmed publisher
Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, et al. Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine. Mol Med. 2016;22: pubmed publisher
Zheng X, Zhang Y, Zhang L, Xu W, Ma W, Sun R, et al. Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation. Biomed Pharmacother. 2016;83:212-220 pubmed publisher
Yuan S, Zhang N, Xu L, Zhou L, Ge X, Guo X, et al. Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus. PLoS ONE. 2016;11:e0156518 pubmed publisher
Zhang J, Chen K, Wang L, Wan X, Shrestha C, Zhou J, et al. Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic ?-cells apoptosis in glucotoxicity through activation of autophagy. Biochem Biophys Res Commun. 2016;476:299-305 pubmed publisher
Liao H, Bao X, Zhu J, Qu J, Sun Y, Ma X, et al. O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway. Chem Biol Interact. 2015;242:91-8 pubmed publisher
Rafiq J, Duno M, Østergaard E, Ravn K, Vissing C, Wibrand F, et al. Exercise Intolerance and Myoglobinuria Associated with a Novel Maternally Inherited MT-ND1 Mutation. JIMD Rep. 2016;25:65-70 pubmed
Lyu J, Zheng G, Chen Z, Wang B, Tao S, Xiang D, et al. Sepsis-induced brain mitochondrial dysfunction is associated with altered mitochondrial Src and PTP1B levels. Brain Res. 2015;1620:130-8 pubmed publisher
Saunders C, Smith L, Wibrand F, Ravn K, Bross P, Thiffault I, et al. CLPB variants associated with autosomal-recessive mitochondrial disorder with cataract, neutropenia, epilepsy, and methylglutaconic aciduria. Am J Hum Genet. 2015;96:258-65 pubmed publisher
Gao S, Li H, Feng X, Li M, Liu Z, Cai Y, et al. α-Enolase plays a catalytically independent role in doxorubicin-induced cardiomyocyte apoptosis and mitochondrial dysfunction. J Mol Cell Cardiol. 2015;79:92-103 pubmed publisher
product information
CatalogNo :
10866-1-AP
AntigenName :
VDAC1/2
Package :
150UL
Price :
99 USD
FullName :
voltage-dependent anion channel 1
Immunogen :
Recombinant Protein
Species :
human, mouse, pieris rapae, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
hVDAC1, Plasmalemmal porin, Porin, PORIN 31 HL, Porin 31HL, Porin 31HM, VDAC, VDAC 1, VDAC1, VDAC2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC008482
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Organelle Marker;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:50 ; IP 1:1000 ; WB 1:1500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.