product summary
request information :
company name :
Novus Biologicals
product type :
antibody
product name :
Sheep Polyclonal GAP43 Antibody
catalog :
NBP1-41123R
quantity :
0.1 ml
price :
315.00 USD
clonality :
polyclonal
host :
sheep
reactivity :
human, dog, rat, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NBP1-41123R
Product Name :
Sheep Polyclonal GAP43 Antibody
List Price :
315.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
Axonal membrane protein GAP-43, B-50, calmodulin-binding protein P-57, Growth-associated protein 43, growth associated protein 43, Neural phosphoprotein B-50, nerve growth-related peptide GAP43, neuromodulin, neuron growth-associated protein 43, pp46, PP46, protein F1
Background :
GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1) is a crucial component for regenerative response in the nervous system that is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific ELAV/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein. Heterozygous GAP-43 knockout mice with GAP-43 levels reduced by one-half display significant memory impairments in cued conditioning or on tests of nociceptive or auditory perception.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Concentration :
1.0 mg/ml
Conjugate :
DyLight 550
Application Summary :
Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen
Host :
Sheep
Immunogen :
GAP43 from rat brain
Localization :
Cell membrane; Peripheral membrane protein; Cytoplasmic side
Marker :
Neuronal Marker
Preservative :
No Preservative
Purity :
IgG purified
CrossReactivity :
Mouse, rat, primate, canine, feline and human.
Storage :
Store at 4C in the dark.
Uses :
This antibody is useful for Western blot analysis where a band can be seen at 43-48 kDa. It is also useful for Immunocytochemistry/Immunofluorescence and immunohistochemistry on frozen sections.
Research Area :
Cancer, Cellular Markers, Growth and Development, Neuroscience, Neuronal Cell Markers
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: usa
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.