product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mouse Monoclonal ATM Antibody
catalog :
NB100-307
quantity :
0.1 ml
price :
309.00 USD
clonality :
monoclonal
host :
mouse
reactivity :
human, rat, mouse
application :
western blot, immunocytochemistry
publications citing this reagent :
  1. Chu P, Yang Y, Lu Y, Chen H, Yu L, Chang M. Silencing of p29 affects DNA damage responses with UV irradiation. Cancer Res. 2006;66:8484-91 pubmed
  2. Bartkova J, Bakkenist C, Rajpert-De Meyts E, Skakkebaek N, Sehested M, Lukas J, et al. ATM activation in normal human tissues and testicular cancer. Cell Cycle. 2005;4:838-45 pubmed
more info or order :
Novus Biologicals product webpage
image
image 1 :
Novus Biologicals NB100-307 image 1
Western Blot: ATM Kinase [Ser 1981][NB100-307]: Western Blot on HeLa crude extract, 5 Gy ionizing radiation.
product information
Catalog Number :
NB100-307
Product Name :
Mouse Monoclonal ATM Antibody
List Price :
309.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
ataxia telangiectasia mutatedATD, ATC, ATDC, ATE, ATA, ataxia telangiectasia mutated (includes complementation groups A, C and D), AT mutated, A-T mutated, AT1, DKFZp781A0353, EC 2.7.11.1, MGC74674, serine-protein kinase ATM, TELO1, TEL1, TEL1, telomere maintenance 1, homolog
Background :
ATM-kinase plays an important regulatory role. DNA damage caused by such things as ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair.
Clonality :
Monoclonal
Clone :
10H11.E12
Application Summary :
Western Blot, Immunocytochemistry/Immunofluorescence
Host :
Mouse
Immunogen :
Synthetic peptide made to a region surrounding the phosphorylated Serine 1981 of human ATM. [UniProt# Q13315]
Isotype :
IgG1 Kappa
Modification :
p Ser1981
Preservative :
0.1% Sodium Azide
Purity :
Ascites
CrossReactivity :
Human, mouse and rat.
Storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Swissprot Human :
Q13315
TMW :
370 kDa
Uses :
This ATM [p Ser1981] (10H11.E12) antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a single band is seen at ~370 kDa.
References Product :
Chu, PC et al. Silencing of p29 Affects DNA Damage Responses with UV Irradiation. Cancer Res. 66: 8484-8491. 2006 [PMID: 16951160] Bartkova, J et al. ATM Activation in Normal Human Tissues Testicular Cancer. Cell Cycle 4:6 e2-e9. 2005 [PMID: 15846060]
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.