product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
mTOR (Ab-2448) Antibody
catalog :
MBS857326
quantity :
0.05 mg
price :
180 USD
clonality :
polyclonal
host :
rabbit
reactivity :
rat, human, mouse
application :
western blot, immunocytochemistry, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS857326
products type :
Antibody
products full name :
mTOR (Ab-2448) Antibody
products short name :
mTOR
other names :
serine/threonine-protein kinase mTOR; Serine/threonine-protein kinase mTOR; serine/threonine-protein kinase mTOR; rapamycin target protein 1; mammalian target of rapamycin; rapamycin and FKBP12 target 1; FKBP-rapamycin associated protein; rapamycin associated protein FRAP2; FKBP12-rapamycin complex-associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; mechanistic target of rapamycin (serine/threonine kinase); FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
products gene name :
mTOR
other gene names :
MTOR; MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; mTOR
uniprot entry name :
MTOR_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
2549
specificity :
mTOR (Ab-2448) Antibody detects endogenous levels of total mTOR protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
50ug/50ul
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100
other info2 :
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S). Pathway: cellcycle Kinase/Phosphatases Akt Translation Insulin/Glucose Jak/Stat
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Albanell J,et al.(2007)Clin Transl Oncol.9(8):484-93. Huang JJ,et al.(2007)Ai Zheng.26(12):1397-403. Kenerson H,et al. (2007)Hum Pathol.38(9):1361-71.
ncbi gi num :
4826730
ncbi acc num :
NP_004949.1
ncbi gb acc num :
NM_004958.3
uniprot acc num :
P42345
ncbi mol weight :
288,892 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!BDNF Signaling Pathway 712093
ncbi summary :
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
size :
0.05 mg
price :
180 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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