catalog number :
MBS853901
products full name :
IkBKA /IKK-alpha Antibody
products short name :
IkBKA /IKK-alpha
other names :
Homo sapiens conserved helix-loop-helix ubiquitous kinase (CHUK), mRNA; Inhibitor of nuclear factor kappa-B kinase subunit alpha; inhibitor of nuclear factor kappa-B kinase subunit alpha; TCF-16; IKK-a kinase; I-kappa-B kinase 1; I-kappa-B kinase-alpha; transcription factor 16; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha; conserved helix-loop-helix ubiquitous kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16
products gene name :
IkBKA /IKK-alpha
other gene names :
CHUK; CHUK; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; IKKA; TCF16; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA; TCF-16
uniprot entry name :
IKKA_HUMAN
form :
Lyophilized rabbit anti- IkBKA purified by peptide affinity column containing 2% BSA and 0.02% NaN3
concentration :
100ug/200ul
tested application :
Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:5,000-1:20,000. Immunohistochemistry: 1:50-200. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal IkBKA (1) antibody was raised against a peptide near intermediate residues of human IkBKA. Reactivity Note: Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) Deneka,M., Neeft,M., Popa,I., et al. Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. EMBO J. 22 (11), 2645-2657 (2003)
ncbi acc num :
NP_001269.3
ncbi gb acc num :
NM_001278
ncbi mol weight :
84,640 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!AKT Phosphorylates Targets In The Cytosol Pathway 106475!!Activated TLR4 Signalling Pathway 106400!!Activation Of NF-kappaB In B Cells Pathway 576251!!Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Alternative NF-kappaB Pathway 138004
ncbi summary :
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]