This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Leptin Receptor Antibody
catalog :
MBS853003
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
catalog number :
MBS853003
products type :
Antibody
products full name :
Leptin Receptor Antibody
products short name :
Leptin Receptor
other names :
leptin receptor isoform 3; Leptin receptor; leptin receptor; huB219; OB receptor; leptin receptor; HuB219; OB receptor; OB-R; CD_antigen: CD295
other gene names :
LEPR; LEPR; OBR; OB-R; CD295; LEP-R; LEPRD; DB; OBR; LEP-R; OB-R
uniprot entry name :
LEPR_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
896
form :
Lyophilized anti-Leptin Receptor antibody purified by protein A column containing 0.02% NaN3
concentration :
100ug/200ul
tested application :
Western Blot (WB)
app notes :
Peptide ELISA titer: 1:40,000-1:80,000. Western blot analysis: 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal Lepti Receptor (1) antibody was raised against a 14 amino acid peptide at the intermediate residues of human Leptin Receptor protein. Reactivity Note: Not yet tested in other species.
other info2 :
Pathway: Leptin Receptor
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1)Koda,M.,Sulkowska,M.,Wincewicz,A. et,al Expression of leptin, leptin receptor, and hypoxia-inducible factor 1 alpha in human endometrial cancer. Ann. N. Y. Acad. Sci. 2007: 1095, 90-98
ncbi gi num :
51093379
ncbi acc num :
NP_001003679.1
ncbi gb acc num :
NM_001003679.3
uniprot acc num :
P48357
ncbi mol weight :
96,042 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Leptin Signaling Pathway 672456
ncbi summary :
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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