catalog number :
MBS851374
products full name :
A1CF Antibody
products short name :
A1CF
other names :
APOBEC1 complementation factor isoform 3; APOBEC1 complementation factor; APOBEC1 complementation factor; apo-B RNA editing protein; APOBEC-1 stimulating protein; apobec-1 complementation factor (ACF) (ASP); APOBEC1 complementation factor; APOBEC1-stimulating protein
products gene name :
A1CF
other gene names :
A1CF; A1CF; ACF; ASP; ACF64; ACF65; APOBEC1CF;
uniprot entry name :
A1CF_HUMAN
form :
Lyophilized A1CF antibody purified by protein A column containing 0.02% NaN3
concentration :
100ug/200ul
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:500-1:1,000. Immunohistochemistry: 1:100-500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal A1CF (1) antibody was raised against a recombinate human A1CF protein 2-122aa (BC054873). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
ncbi gb acc num :
NM_001198820.1
ncbi mol weight :
58,871 Da
ncbi pathways :
Formation Of The Editosome Pathway 106577!!Gene Expression Pathway 105937!!MRNA Editing Pathway 106575!!MRNA Editing: C To U Conversion Pathway 106576
ncbi summary :
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]