This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
CD49b antibody
catalog :
MBS535479
quantity :
0.05 mg
price :
540 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS535479
products type :
Antibody
products full name :
CD49b antibody
products short name :
CD49b
products name syn :
Polyclonal CD49b; Anti-CD49b; platelet membrane glycoprotein ia; integrin alpha 2; alpha2 integrin; CDb 49; VLA2a; cd49b; CDb-49; CD49b; integrin alpha2
other names :
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), isoform CRA_a; Integrin alpha-2; integrin alpha-2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD_antigen: CD49b
products gene name :
CD49b
other gene names :
ITGA2; ITGA2; BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; CD49B; GPIa
uniprot entry name :
ITA2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
To be determined by end-user
sequence length :
1181
specificity :
Human
purity :
CD49B antibody was purified by affinity chromatography.
form :
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
IHC-P: 10 ug/ml
other info1 :
Biological Significance: The CD49b protein is an integrin alpha subunit. It makes up half of the alpha2Beta1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: CD49B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
products categories :
Immunology
products description :
Rabbit polyclonal CD49b antibody
ncbi gi num :
119575267
ncbi acc num :
EAW54872.1
uniprot acc num :
P17301
ncbi mol weight :
129,295 Da
ncbi pathways :
Arf6 Trafficking Events Pathway 137954!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Axon Guidance Pathway 105688!!CHL1 Interactions Pathway 161007!!CXCR4-mediated Signaling Events Pathway 137910!!Developmental Biology Pathway 477129!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285
ncbi summary :
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
size :
0.05 mg
price :
540 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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