This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Androgen Receptor antibody
catalog :
MBS535341
quantity :
0.1 mg
price :
745 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
catalog number :
MBS535341
products type :
Antibody
products full name :
Androgen Receptor antibody
products short name :
Androgen Receptor
products name syn :
Polyclonal Androgen Receptor; Anti-Androgen Receptor; AR
other names :
androgen receptor; Androgen receptor; androgen receptor; androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
other gene names :
AR; AR; KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; DHTR; NR3C4
uniprot entry name :
ANDR_HUMAN
clonality :
Polyclonal
isotype :
IgG1
host :
Rabbit
reactivity :
To be determined by end - user
sequence length :
917
specificity :
Human
purity :
Androgen Receptor antibody was purified by affinity chromatography.
form :
Purified IgG supplied in PBS with 0.05% NaN3.
concentration :
1.0 mg/ml
storage stability :
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 2 ug/ml
other info1 :
Biological Significance: Androgen receptors (AR) have been found in a variety of tissues, including reproductive organs, central nervous system and skeletal muscle. These stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Androgen receptor antibody was raised in rabbit using a synthetic peptide corresponding to residues M(1) E V Q L G L G R V Y P R P P S K T Y R G(21) C of human androgen receptor as the immunogen.
products categories :
Hormones & Steroids
products description :
Rabbit polyclonal Androgen Receptor antibody
ncbi gi num :
178882
ncbi acc num :
AAA51772.1
uniprot acc num :
P10275
ncbi mol weight :
44,643 Da
ncbi pathways :
Activated PKN1 Stimulates Transcription Of AR (androgen Receptor) Regulated Genes KLK2 And KLK3 Pathway 1183588!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Androgen Receptor Signaling Pathway 198806!!Coregulation Of Androgen Receptor Activity Pathway 138085!!FOXA1 Transcription Factor Network Pathway 137979!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!IL-6 Signaling Pathway 198864!!Integrated Breast Cancer Pathway 219801!!Integrated Pancreatic Cancer Pathway 711360
ncbi summary :
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
745 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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