catalog number :
MBS534518
products full name :
Collagen Type IV antibody (biotin)
products short name :
Collagen Type IV
products name syn :
Polyclonal Collagen Type IV; Anti-Collagen Type IV; Collagen Of Basement Membrane alpha 1 Chain; Canstatin; Arresten
other names :
collagen type IV alpha 5 chain, partial; Collagen alpha-5(IV) chain; collagen alpha-5(IV) chain; collagen, type IV, alpha 5
other gene names :
COL4A5; COL4A5; ATS; ASLN; CA54
uniprot entry name :
CO4A5_HUMAN
reactivity :
To be determined by end-user
specificity :
Bovine/Human collagen type IV
purity :
Collagen Type IV antibody (biotin) was purified by affinity chromatography.
form :
Lyophilized from 0.125M Na3B4O7, pH 8.0, with 0.075M NaCl, 0.005M EDTA, 10 mg/ml BSA, and 0.01% NaN3. Immunoglobulin and protease free.
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
ELISA: 1:20,000-1:100,000. IHC: 1:1,000-1:5,000. WB: 1:2,000-1:10,000
other info1 :
Bioactivity: Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Tag/Conjugate: Biotin. Immunogen: Collagen type IV antibody (biotin) was raised in rabbit using collagen type IV from human and bovine placenta as the immunogen.
products categories :
Cell Biology ; Conjugated Polyclonal Antibodies
products description :
Rabbit polyclonal Collagen Type IV antibody (biotin) conjugated
ncbi acc num :
AAD13909.1
ncbi mol weight :
161,632 Da
ncbi pathways :
Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Axon Guidance Pathway 105688!!Collagen Biosynthesis And Modifying Enzymes Pathway 645289!!Collagen Formation Pathway 645288!!Developmental Biology Pathway 477129!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Extracellular Matrix Organization Pathway 576262
ncbi summary :
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]