catalog number :
MBS531822
products full name :
Heme Oxygenase 1 antibody
products short name :
Heme Oxygenase 1
products name syn :
Monoclonal Heme Oxygenase 1; Anti-Heme Oxygenase 1; Heme Oxygenase-1; HO-1-1
other names :
heme oxygenase 1; Heme oxygenase 1; heme oxygenase 1; heme oxygenase 1
other gene names :
HMOX1; HMOX1; HO-1; HSP32; HMOX1D; bK286B10; HO; HO1; HO-1
uniprot entry name :
HMOX1_HUMAN
reactivity :
Bovine, Dog, Mouse, Rat
purity :
Heme Oxygenase 1 antibody was purified by Protein G affinity chromatography.
form :
PBS with 50% glycerol, and 0.09% NaN3.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Flow Cytometry (FC/FACS), IC, Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
app notes :
FC: 10 ug/ml. WB: 1:250
other info1 :
Biological Significance: Heme oxygenase (HO) is an enzyme that catalyzes the degradation of heme. This produces biliverdin, iron, and carbon monoxide.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Heme Oxygenase 1 antibody was raised in mouse using a synthetic peptide corresponding to the sequence near the N-terminus of human HO-1 as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal Heme Oxygenase 1 antibody
ncbi acc num :
NP_002124.1
ncbi gb acc num :
NM_002133.2
ncbi mol weight :
32,819 Da
ncbi pathways :
HIF-1 Signaling Pathway 695200!!HIF-1-alpha Transcription Factor Network Pathway 138045!!Heme Degradation Pathway 160971!!Iron Uptake And Transport Pathway 187191!!Keap1-Nrf2 Pathway 198777!!Metabolism Pathway 477135!!Metabolism Of Porphyrins Pathway 106325!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!Mineral Absorption Pathway 212237
ncbi summary :
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]