catalog number :
MBS530277
products full name :
P Glycoprotein antibody
products short name :
P Glycoprotein
products name syn :
Monoclonal P Glycoprotein; Anti-P Glycoprotein; P-Glycoprotein; P Glycoprotein; Anti P Glycoprotein
other names :
glycoprotein; glycoprotein
reactivity :
To be determined by end-user
purity :
P Glycoprotein antibody was purified by affinity chromatography.
form :
PBS, with protein stabilizer, and 0.1% NaN3.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
app notes :
FC: 5 x 10^5 pelleted cells per 50 uL of 10-100 ug/mL. IHC: 0.1-10 ug/ml. IP: 25-50 ug/ml
other info1 :
Biological Significance: Human P-glycoprotein is a multidrug resistance (MDR1) product that acts as an ATP-dependent efflux pump to remove drugs and other potentially harmful products from the cell interior. Research has linked multidrug resistance in cancer cells to the overexpression of P-glycoprotein.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: P Glycoprotein antibody was raised in mouse using adriamycin-resistant human myelogenous leukemia K-562/ADM cells as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal P Glycoprotein antibody
ncbi acc num :
NP_478342.1
ncbi gb acc num :
NC_003243.1
ncbi mol weight :
170 kDa (predicted detection band MW)