catalog number :
MBS530147
products full name :
CFTR antibody
products short name :
CFTR
products name syn :
Monoclonal CFTR; Anti-CFTR; Cystic Fibrosis Transmembrane Conductance Regulator
other names :
cystic fibrosis transmembrane conductance regulator, partial; Cystic fibrosis transmembrane conductance regulator; Cystic fibrosis transmembrane conductance regulator
products gene name :
CFTR
uniprot entry name :
Q9NP06_HUMAN
reactivity :
To be determined by end-user
purity :
CFTR antibody was purified by Protein A chromatography.
form :
Protein G purified antibody supplied in 100mM Tris-glycine, pH 7.4, with 0.15M NaCl, and 0.05% NaN3.
storage stability :
Store at 4 degree C.
tested application :
Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)
other info1 :
Biological Significance: CFTR (Cystic Fibrosis Transmembrane conductance Regulator) is a 170 kDa chloride (Cl-) channel that regulates salt and water transport across epithelial tissues, where it modulates production of mucus, sweat, saliva, tears, and digestive enzymes. Cystic fibrosis patients have mutations in this protein, resulting in defective ion transport.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: CFTR antibody was raised in mouse using a synthetic peptide(RKGYRQRLELSD) corresponding to residues 25-36 of human cystic fibrosis transmembrane conductance regulator (CFTR) as the immunogen.
products categories :
Signal Transduction
products description :
Mouse monoclonal CFTR antibody
ncbi acc num :
AAB20219.2
ncbi mol weight :
170 kDa (predicted detection band MW)