This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Anti-Mouse CD25, Purified (Clone PC61.5.3) (rat IgG1)
catalog :
MBS520081
quantity :
0.25 mg
price :
255 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
PC61.5.3
application :
immunohistochemistry, immunoprecipitation, flow cytometry
product information
catalog number :
MBS520081
products type :
Antibody
products full name :
Anti-Mouse CD25, Purified (Clone PC61.5.3) (rat IgG1)
products short name :
CD25
products name syn :
CD25, Purified (Clone PC61.5.3) (rat IgG1); Purified Anti-Mouse CD25 (IL-2R) Monoclonal Antibody
other names :
CD25; Peripheral myelin protein 22; Protein CD25; SR13 myelin protein; Schwann cell membrane glycoprotein
products gene name :
CD25
other gene names :
Pmp22; Cd25; Pmp-22; PMP-22; SAG
uniprot entry name :
PMP22_RAT
clonality :
Monoclonal
isotype :
Rat IgG1
clone :
PC61.5.3
host :
Rat
reactivity :
Mouse
sequence length :
160
specificity :
CD25 (IL-2Ra, p55, Ly 43) (Mouse CD25 (IL-2 receptor, a chain))
form :
Purified (Purified Ig buffered in PBS and 0.02% NaN3. (Purified from bioreactor material via Protein G Chromatography))
concentration :
Antibody Concentration: 1.0 mg/ml
storage stability :
Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC), Flow Cytometry (FC), Immunoprecipitation (IP), Functional Assay (FA)
other info1 :
Immunogen: B6.1 CTL Cell line. Donor: OFA rat spleen. Fusion Partner: mouse myeloma line P3X63Ag8.653
other info2 :
Presentation: 250 ug purified Ig buffered in PBS and 0.02% NaN3
products description :
anti-mouse CD25 (IL-2R) monoclonal antibody reacts with the low affinity alpha chain of the interleukin-2 receptor antigen present on activated T and B cells in mice. MBS520081 inhibits IL-2 binding and IL-2 dependent proliferation. Applications include flow cytometry and immunoprecipitation. (1,2,3). This clone has also been referenced to work in immunohistochemistry (4).
ncbi gi num :
55904
ncbi acc num :
CAA44297.1
uniprot acc num :
P25094
ncbi mol weight :
17,946 Da
uniprot summary :
Function: Might be involved in growth regulation, and in myelinization in the peripheral nervous system. Subcellular location: Cell membrane; Multi-pass membrane protein . By similarity. Tissue specificity: Found exclusively in the peripheral nervous system. Present in both myelinating and nonmyelinating Schwann cells. Found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). Ref.4. Developmental stage: Levels increase between embryonic day 21 (E21) and postnatal day 0 (PND0) and then gradually increase up to PND15. There is a slight increase between PND15 and adulthood. Ref.4. Induction: Strongly down-regulated in the initial phase after sciatic nerve injury. Sequence similarities: Belongs to the PMP-22/EMP/MP20 family.
size :
0.25 mg
price :
255 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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