This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
beta-Tubulin (a.a. 168-177)
catalog :
MBS472008
quantity :
0.1 ml
price :
280 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunocytochemistry
product information
catalog number :
MBS472008
products type :
Antibody
products full name :
beta-Tubulin (a.a. 168-177)
products short name :
beta-Tubulin
products name syn :
Tubulin beta
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Rat, Mouse, Chicken
specificity :
This antibody was affinity purified using bIII-Tubulin (a.a.168-177) peptide (without carrier). This antibody detects a 50 kDa* protein corresponding to the molecular mass of b-Tubulin on SDS-PAGE immunoblots of purified brain tubulin and mouse brain tissue.
purity :
Affinity Purified
form :
Rabbit polyclonal, affinity-purified antibody is supplied in 100 ul phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide.
storage stability :
Store at -20 degree C. Do not aliquot. Stable for 1 year.
tested application :
ELISA, Western Blot, Immunocytochemistry
app notes :
ELISA: 1:2000. Immunocytochemistry: 1:50. Western Blot: 1:1000
other info1 :
Immunogen: bIII-Tubulin (a.a. 168-177) synthetic peptide (coupled to KLH) corresponding to amino acid residues from human bIII-tubulin. This sequence is identical to similar regions in bI, bII, and bIII-tubulin isotypes, and is well conserved in tubulins from most eukaryotic species.
products description :
Microtubules (MTs) are cytoskeletal elements that play an essential role in cell division and cytoplasmic organization. MTs are dynamic polymers of a/b-tubulin heterodimers. At least two populations of MTs, called dynamic and stable according to their rates of turnover, are readily distinguishable in cells. The proteins associated with MTs (MAPs) are among the bestknown factors that regulate MT dynamics and stability. In addition, a variety of different post-translational modifications may also regulate MT dynamics and stability. Phosphorylation is one of these modifications and it can occur on serine, threonine, and tyrosine residues in b-tubulin isoforms. Multiple kinases can phosphorylate Ser-444 at the C-terminus of bIII-tubulin in vitro. Unphosphorylated Ser-444 in bIII-tubulin is an early marker for cells of neuronal lineage, while phosphorylation of Ser-444 is upregulated after neuronal maturation and may preferentially occur in assembled MTs. By contrast, Cdk1 phosphorylation of Ser-172 in btubulin occurs in mitotic cells and may impair tubulin incorporation into microtubules.
products references :
Fourest-Lieuvin, A. et al. (2006) Mol. Biol. Cell. 17(3):1041. Westermann, S. & Weber, K. (2003) Nat. Rev. Mol. Cell. Biol. 4:938. Fanarraga, M.L. et al. (1999) Eur. J. Neurosci. 11:517. Diaz-Nido, J. et al. (1990) J Biol. Chem. 265(23):13949.
size :
0.1 ml
price :
280 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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