catalog number :
MBS421164
products full name :
Goat anti-RBP4 Antibody
products short name :
RBP4
products name syn :
RBP4; retinol binding protein 4; plasma; retinol-binding protein 4; interstitial; retinol-binding protein 4; plasma; Goat Anti-RBP4 (Internal); RBP4; retinol binding protein 4, plasma; retinol-binding protein 4, interstitial; retinol-binding protein 4, plasma
other names :
retinol-binding protein 4; Retinol-binding protein 4; retinol-binding protein 4; RBP; PRBP; plasma retinol-binding protein; retinol-binding protein 4, interstitial; retinol binding protein 4, plasma; Plasma retinol-binding protein; PRBP; RBP
products gene name :
RBP4
other gene names :
RBP4; RBP4; RDCCAS; PRBP; RBP
uniprot entry name :
RET4_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
QKGNDDHWIVDTDYD
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 22kDa band observed in human liver and skin lysates (calculated MW of 23.0kDa according to NP_006735.2). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QKGNDDHWIVDTDYD, from the internal region of the protein sequence according to NP_006735.2.
ncbi acc num :
NP_006735.2
ncbi gb acc num :
NM_006744.3
ncbi mol weight :
23,010 Da
ncbi pathways :
Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Retinoid Cycle Disease Events Pathway 771582!!Retinoid Metabolism And Transport Pathway 187208!!SREBP Signalling Pathway 219802!!Signal Transduction Pathway 477114!!The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway 771585!!Visual Phototransduction Pathway 771584!!Vitamin A And Carotenoid Metabolism Pathway 198785!!Retinoate Biosynthesis I Pathway 545452
ncbi summary :
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]