catalog number :
MBS420941
products full name :
Goat anti-EP4 prostaglandin receptor Antibody
products short name :
EP4 prostaglandin receptor
products name syn :
prostaglandin E receptor 4 (subtype EP4); MGC126583; PTGER4; EP4; EP4R; PGE receptor; EP4 subtype prostaglandin E receptor 4; subtype EP4; prostaglandin E2 receptor; prostaglandin E receptor 4 (subtype EP4); MGC126583; PTGER4; EP4; EP4R; PGE receptor, EP4 subtype prostaglandin E receptor 4, subtype EP4; prostaglandin E2 receptor
other names :
prostaglandin E2 receptor EP4 subtype; Prostaglandin E2 receptor EP4 subtype; prostaglandin E2 receptor EP4 subtype; prostanoid EP4 receptor; PGE receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E receptor 4 (subtype EP4); Prostanoid EP4 receptor
products gene name :
PTGER4
other gene names :
PTGER4; PTGER4; EP4; EP4R; PTGER2; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype
uniprot entry name :
PE2R4_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 55kDa band observed in Human Testes lysates (calculated MW of 53.1kDa according to NP_000949.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-LEREVSKNPDLQA, from the internal region of the protein sequence according to NP_000949.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426159
ncbi acc num :
NP_000949.1
ncbi gb acc num :
NM_000958.2
ncbi mol weight :
53,119 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Eicosanoid Ligand-binding Receptors Pathway 106370!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Inflammatory Mediator Regulation Of TRP Channels Pathway 948277!!Inflammatory Mediator Regulation Of TRP Channels Pathway 948307!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462
ncbi summary :
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]