Goat anti-GSTM1 / GSTM2 Antibody | MyBioSource MBS420063 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-GSTM1 / GSTM2 Antibody

catalog :

MBS420063

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, enzyme immunoassay

product information

catalog number :

MBS420063

products type :

Antibody

products full name :

Goat anti-GSTM1 / GSTM2 Antibody

products short name :

GSTM1/GSTM2

products name syn :

GSTM1; GSTM2; MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; MGC26563; GSTM1a-1a; GSTM1b-1b; glutathione S-transferase M1; HB subunit 4; GST class-mu 1; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathione S-transferase; Mu-1; glutathione S-aralkyltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-transferase mu 1; glutathione S-transferase mu 2 (muscle); GST4; GSTM; GSTM2-2; GTHMUS; MGC117303; GST class-mu 2; GST; muscle; S-(hydroxyalkyl)glutathione lyase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; glutathione S-aryltransferase M2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-transferase M2 (muscle); glutathione S-transferase mu 2; GSTM1; GSTM2; MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; MGC26563; GSTM1a-1a; GSTM1b-1b; glutathione S-transferase M1; HB subunit 4; GST class-mu 1; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathione S-transferase, Mu-1; glutathione S-aralkyltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-transferase mu 1; glutathione S-transferase mu 2 (muscle); GST4; GSTM; GSTM2-2; GTHMUS; MGC117303; GST class-mu 2; GST, muscle; S-(hydroxyalkyl)glutathione lyase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; glutathione S-aryltransferase M2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-transferase M2 (muscle); glutathione S-transferase mu 2

other names :

glutathione S-transferase Mu 1 isoform 1; Glutathione S-transferase Mu 1; glutathione S-transferase Mu 1; HB subunit 4; GST class-mu 1; GST HB subunit 4; glutathione S-transferase M1; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; S-(hydroxyalkyl)glutathione lyase; glutathione S-transferase mu 1; GST HB subunit 4; GST class-mu 1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4

products gene name :

GSTM1/GSTM2

other gene names :

GSTM1; GSTM1; MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GST1

uniprot entry name :

GSTM1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human

sequence length :

218

sequence :

CVFSKMAVWGNK

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: Approx 26kDa band observed in Human Liver and Human Lung lysates (calculated MW of 25.7kDa according to NP_000552.2, and NP_000839.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.

other info1 :

Epitope: C Terminus. Immunogen: Peptide with sequence CVFSKMAVWGNK, from the C Terminus of the protein sequence according to NP_000552.2; NP_666533.1; NP_000839.1. Corresponding Immunizing Peptide: Catalog #MBS425838

other info2 :

Important Note: This antibody is expected to recognise both reported variants of human GSTM1 protein (NP_000552.2; NP_666533.1) and wil also recognise human GSTM2 protein (NP_000839.1).

ncbi gi num :

23065544

ncbi acc num :

NP_000552.2

ncbi gb acc num :

NM_000561.3

ncbi mol weight :

21,253 Da

ncbi pathways :

Aflatoxin B1 Metabolism Pathway 198808!!Biological Oxidations Pathway 105698!!C-MYB Transcription Factor Network Pathway 138073!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Drug Metabolism - Cytochrome P450 Pathway 83032!!Drug Metabolism - Cytochrome P450 Pathway 427!!Estrogen Metabolism Pathway 198898!!Glutathione Conjugation Pathway 105727!!Glutathione Metabolism Pathway 82973

ncbi summary :

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

290 USD