catalog number :
MBS315474
products full name :
Goat anti Apo (a)
products short name :
Apolipoprotein (a) (Apo (a))-LDL adsorbed/Plasminogen Stripped
products name syn :
Goat Antibody to Human Apolipoprotein(a), (Apo(a))
other names :
apolipoprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244; apolipoprotein A-II; Apolipoprotein A2
other gene names :
APOA2; APOA2; apoAII; Apo-AII; ApoA-II
uniprot entry name :
APOA2_HUMAN
specificity :
Apolipoprotein (a) (Apo (a))-LDL adsorbed/Plasminogen Stripped
purity :
Liquid phase adsorption of neat serum with human LDL. Liquid/solid phase absorption with plasminogen/d>1.21 plasma fraction. Affinity chromatography over Lp(a)-Sepharose (bound fraction). Cross-reactivity to plasminogen reduced by liquid phase ab
form :
Affinity Purified, Liquid
concentration :
1060ug/ml (Lowry)
storage stability :
Short-term (up to 2 months unopened) store at 2 to 8 degree C. Long term store at -20 degree C.
other info1 :
Immunogen: Human Lp(a)
other info2 :
Buffer: 10mM Tris, 100mM Sodium chloride, 1mM EDTA, pH 7.4. Preservative: 0.01% Sodium azide. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Polyclonal Antibodies to Lipoproteins
products references :
Caplice, N.M., et al., (2001), "Lipoprotein(a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis", Blood, 98: 2980-2987. Bonen, D.K., et al., (1998), "Inhibition of N-linked g
ncbi acc num :
CAA28583.1
ncbi mol weight :
11,175 Da
ncbi pathways :
Chylomicron-mediated Lipid Transport Pathway 106157!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450!!Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway 119544!!Statin Pathway 198852
ncbi summary :
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]
uniprot summary :
Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16