product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-Human Bone Morphogenetic Protein (BMP4) Polyclonal Antibody
catalog :
MBS300978
quantity :
0.1 ml
price :
170 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS300978
products type :
Antibody
products full name :
Rabbit Anti-Human Bone Morphogenetic Protein (BMP4) Polyclonal Antibody
products short name :
Bone Morphogenetic Protein 4
other names :
bone morphogenetic protein 4 preproprotein; Bone morphogenetic protein 4; bone morphogenetic protein 4; BMP-2B; BMP-4; bone morphogenetic protein 2B; bone morphogenetic protein 4; Bone morphogenetic protein 2B; BMP-2B
products gene name :
BMP-4
other gene names :
BMP4; BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP2B; DVR4; BMP-4; BMP-2B
uniprot entry name :
BMP4_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
408
form :
0.1 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
storage stability :
Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
Immunohistochemistry Procedure . Specimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:50. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system. Immunohistochemistry Dilution: 1:50. IHC Positive Control: Bone Marrow
other info2 :
Immunogen: Recombinant human BMP-4 protein. Control Tissue: Bone Marrow. Cellular Localization: Cytoplasm. Entrez Gene Code: 652. Pathway: Growth Factor and Hormone
products description :
Bone morphogenetic protein 4 (BMP4) is one of nine structurally related BMPs belonging to the transforming growth factor beta superfamily of secreted proteins. BMP4 has important roles as a signaling molecule in the developing central and peripheral nervous system, musculature and skeleton. BMP also plays an important role in early tooth morphogenesis.
ncbi gi num :
157276593
ncbi acc num :
NP_001193.2
ncbi gb acc num :
NM_001202.3
ncbi mol weight :
45 kDa
ncbi pathways :
Adipogenesis Pathway 198832!!BMP Signaling Pathway 1084755!!BMP Signaling Pathway 1108218!!Basal Cell Carcinoma Pathway 83113!!Basal Cell Carcinoma Pathway 525!!Cardiac Progenitor Differentiation Pathway 712094!!Elastic Fibre Formation Pathway 730310!!Extracellular Matrix Organization Pathway 576262!!Glypican 3 Network Pathway 138084!!Heart Development Pathway 198802
ncbi summary :
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
170 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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