This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Catalase antibody, Internal
catalog :
MBS277036
quantity :
0.1 ml
price :
360 USD
clonality :
polyclonal
host :
rabbit
reactivity :
western clawed frog, human, rat, dog, cow, zebrafish
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS277036
products type :
Antibody
products full name :
Catalase antibody, Internal
products short name :
Catalase
products name syn :
catalase; MGC138422 antibody; MGC138424 antibody; CAT antibody; catalase antibody
other names :
catalase; Catalase; catalase; catalase
products gene name :
CAT
other gene names :
CAT; CAT
uniprot entry name :
CATA_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human. Predicted Reactivity: Mouse (93%), Dog (95%), Pig (94%), Rat (92%), Xenopus laevis (84%), Zebrafish (82%), Bovine (93%), Xenopus tropicalis (84%)
sequence length :
527
purity :
Purified by antigen-affinity chromatography.
form :
Liquid
concentration :
1 mg/ml
storage stability :
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
app notes :
IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000. Western blot: 1:500-1:3000. IHC (Formalin-fixed paraffin-embedded sections): suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0). Optimal dilutions/concentrations should be determined by the researcher.
other info1 :
Cellular Localization: Peroxisome. Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size: 60 kDa. Positive Controls: Molt-4, Raji
other info2 :
Immunogen: Recombinant fragment corresponding to a region within amino acids 89 and 341 of Catalase (Uniprot ID#P04040). Research Area: Cancer; Type of cancer; Breast; Ductal; Cancer; Type of cancer; Gastrointestinal; Stomach; Cancer; Type of cancer; Prostate cancer; Cancer; Type of cancer; Skin; Squamous cell
products description :
Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer s disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]. Product Description: Rabbit Polyclonal antibody to Catalase (catalase)
ncbi gi num :
4557014
ncbi acc num :
NP_001743
ncbi gb acc num :
NM_001752
uniprot acc num :
P04040
ncbi mol weight :
59,756 Da
ncbi pathways :
Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Cellular Responses To Stress Pathway 645258!!DNA Damage Response (only ATM Dependent) Pathway 198827!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Folate Metabolism Pathway 198833!!FoxO Family Signaling Pathway 138036!!FoxO Signaling Pathway 921162!!Glyoxylate And Dicarboxylate Metabolism Pathway 83002
ncbi summary :
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
size :
0.1 ml
price :
360 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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