O-GlcNAc transferase antibody [N1N2], N-term | MyBioSource MBS274885 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

O-GlcNAc transferase antibody [N1N2], N-term

catalog :

MBS274885

quantity :

0.1 ml

price :

360 USD

clonality :

polyclonal

host :

rabbit

reactivity :

western clawed frog, human, mouse, cow

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

catalog number :

MBS274885

products type :

Antibody

products full name :

O-GlcNAc transferase antibody [N1N2], N-term

products short name :

O-GlcNAc transferase

products name syn :

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); FLJ23071 antibody; HRNT1 antibody; MGC22921 antibody; O-GLCNAC antibody; OGT antibody; O-GlcNAc transferase p110 subunit antibody; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase antibody; O-GlcNAc transferase subunit p110 antibody; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit antibody; O-linked N-acetylglucosamine transferase 110 kDa subunit antibody; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) antibody

other names :

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform 1; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; O-GlcNAc transferase p110 subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); O-linked N-acetylglucosamine transferase 110 kDa subunit; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase; O-linked N-acetylglucosamine (GlcNAc) transferase; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT

products gene name :

OGT

other gene names :

OGT; OGT; HRNT1; O-GLCNAC; OGT

uniprot entry name :

OGT1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse. Predicted Reactivity: Rat (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Bovine (100%)

sequence length :

665

purity :

Purified by antigen-affinity chromatography.

form :

Liquid

concentration :

1 mg/ml

storage stability :

Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.

tested application :

Immunohistochemistry (IHC) Paraffin, Western Blot (WB)

app notes :

IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000. Western blot: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher.

other info1 :

Cellular Localization: Cytoplasm (Potential), Nucleus. Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size: 117 kDa. Positive Controls: HeLa, mouse brain

other info2 :

Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 280 of O-GlcNAc transferase (Uniprot ID#O15294). Antigen Species: Human. Research Area: Cell Biology; Post-translational modification; Glycosylation O-linked; Signal Transduction; O-link glycosylation

products description :

Background: O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]. Product Description: Rabbit Polyclonal antibody to O-GlcNAc transferase (O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase))

ncbi gi num :

32307148

ncbi acc num :

NP_858058

ncbi gb acc num :

NM_181672

uniprot acc num :

O15294

ncbi mol weight :

74,536 Da

ncbi pathways :

Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!HATs Acetylate Histones Pathway 1127683!!Other Types Of O-glycan Biosynthesis Pathway 82978!!Other Types Of O-glycan Biosynthesis Pathway 349!!Protein O-[N-acetyl]-glucosylation Pathway 1108787!!Protein O-[N-acetyl]-glucosylation Pathway 982231

ncbi summary :

This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

size :

0.1 ml

price :

360 USD