catalog number :
MBS274501
products full name :
14-3-3 eta antibody
products short name :
14-3-3 eta
products name syn :
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta polypeptide; YWHA1 antibody; YWHAH antibody; 14-3-3 protein eta antibody; 14-3-3 eta antibody; "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta polypeptide antibody
other names :
14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; Protein AS1
products gene name :
YWHAH
other gene names :
YWHAH; YWHAH; YWHA1; YWHA1
uniprot entry name :
1433F_HUMAN
reactivity :
Human. Predicted Reactivity: Mouse (100%), Rat (100%), Xenopus laevis (93%), Xenopus Tropicalis (100%), Rabbit (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
purity :
Purified by antigen-affinity chromatography.
storage stability :
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
app notes :
ICC/IF: 1:100-1:1000. IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000. Western blot: 1:500-1:3000. IHC (Formalin-fixed paraffin-embedded sections): suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0). Optimal dilutions/concentrations should be determined by the researcher.
other info1 :
Storage Buffer: 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size: 28 kDa. Positive Controls: HCT116
other info2 :
Immunogen: Synthetic peptide corresponding to a region within amino acids 26 and 120 of 14-3-3 eta (Uniprot ID#Q04917). Antigen Species: Human. Research Area: Cancer; Type of cancer; Breast; Other; Stem Cell Development; Development; Morphogenesis
products description :
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. [provided by RefSeq]. Product Description: Rabbit Polyclonal antibody to 14-3-3 eta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide)
ncbi gb acc num :
NM_003405
ncbi mol weight :
28,219 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Apoptosis Pathway 105648!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020!!Epstein-Barr Virus Infection Pathway 585562
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]