catalog number :
MBS240493
products full name :
Rabbit Polyclonal to Human Adiponectin
products short name :
Adiponectin
products name syn :
Anti-Adiponectin Antibody (C-Terminus) IHC-plus; Adiponectin; ADPN; ACDC; ADIPQTL1; APM-1; APM1; ACRP30; Gelatin-binding protein 28; GBP28; Gelatin-binding protein; Human Adiponectin
other names :
adiponectin; Adiponectin; adiponectin; gelatin-binding protein 28; adipose specific collagen-like factor; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipose most abundant gene transcript 1 protein; adiponectin, C1Q and collagen domain containing; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1; Gelatin-binding protein
products gene name :
ADIPOQ
other gene names :
ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28; ACRP30; apM-1
uniprot entry name :
ADIPO_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
15 amino acid peptide from near the carboxy-terminus of human adiponectin
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide.
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (2.5 ug/ml), WB (1 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human ADIPOQ / Adiponectin.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: Adiponectin antibody was raised against synthetic peptide from human ADIPOQ / Adiponectin. Antigen Modification: C-Terminus
products description :
Adiponectin/APM1 is a hormone secreted by adipocytes that regulates energy homeostasis and glucose and lipid metabolism. APM1 gene is exclusively expressed in adipose tissue. The protein, also known as gelatin-binding protein, has high similarity with collagens X and VIII and complement factor C1q. It is proposed that APM1 protein may be a collagen-like secretory protein.
ncbi acc num :
NP_004788.1
ncbi gb acc num :
NM_004797.3
ncbi mol weight :
26,414 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198832!!Developmental Biology Pathway 477129!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862188!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862314!!PPAR Signaling Pathway 83042
ncbi summary :
This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]