catalog number :
MBS240262
products full name :
Rabbit Polyclonal to Human PPARG / PPAR Gamma
products short name :
PPARG / PPAR Gamma
products name syn :
Anti-PPARG / PPAR Gamma Antibody (Internal) IHC-plus; PPARG; NR1C3; PPAR gamma; PPAR gamma 2; PPARG1; PPARG2; PPARgamma; CIMT1; GLM1; PPAR-gamma; Human PPARG; PPAR Gamma
other names :
peroxisome proliferator-activated receptor gamma isoform 2; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma; PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3
products gene name :
PPARG
other gene names :
PPARG; PPARG; GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; NR1C3; PPAR-gamma
uniprot entry name :
PPARG_HUMAN
reactivity :
Boar, Dog, Duck, Guinea pig, Hamster, Human, Macaque, Mink, Mouse, Orangutan, Rabbit, Rat, Squirrel
specificity :
Amino acids 255 -268 of human PPAR gamma isoform 1.
purity :
Immunoaffinity Purified
form :
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:8000 - 1:32000), IHC-P (5 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human PPARG.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: PPARG / PPAR Gamma antibody was raised against synthetic peptide from human PPARG. Antigen Modification: Internal
products categories :
Family: NHR. Subfamily: NR1 Thyroid hormone-like
products description :
Peroxisome proliferator-activated receptor gamma (PPAR gamma), a NR1 Thyroid Hormone-Like Receptor, is a transcription factor that regulates genes involved in lipid metabolism and adipocyte differentiation and has been shown to affect placental differentiation and cell proliferation and differentiation pathways in various diseases such as Type II diabetes and atherosclerosis. Recently, PPAR gamma has been suggested to affect inflammatory digestive diseases (Dubuquoy et al. 2002).
ncbi acc num :
NP_056953.2
ncbi gb acc num :
NM_015869.4
ncbi mol weight :
21,580 Da
ncbi pathways :
AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipogenesis Pathway 198832!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Developmental Biology Pathway 477129!!Energy Metabolism Pathway 198907!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Huntington's Disease Pathway 83100
ncbi summary :
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]