RABBIT ANTI PPAR GAMMA | MyBioSource MBS221541 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

RABBIT ANTI PPAR GAMMA

catalog :

MBS221541

quantity :

0.05 mg

price :

390 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog

application :

enzyme immunoassay

product information

catalog number :

MBS221541

products type :

Antibody

products full name :

RABBIT ANTI PPAR GAMMA

products short name :

PPAR GAMMA

other names :

peroxisome proliferator-activated receptor gamma isoform 1; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma; PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3

products gene name :

PPAR GAMMA

other gene names :

PPARG; PPARG; GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; NR1C3; PPAR-gamma

uniprot entry name :

PPARG_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Dog (Expected from Sequence), Duck (Expected from Sequence), Guinea Pig (Expected from Sequence), Hamster (Expected from Sequence), Macaque (Expected from Sequence), Mink (Expected from Sequence), Mouse (Expected from Sequence), Rabbit (Expected from Sequ

sequence length :

477

specificity :

This item detects human peroxisome proliferator-activated receptor ? (PPARG), a member of the nuclear hormone receptor subfamily of transcription factors. Upon activation, PPARG forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARG is principally involved in the cellular assimilation of lipids, with key roles in adipocyte differentiation and adipogenesis. Two alternatively spliced isoforms of PPARG exist, termed PPARG1 and PPARG2, which are identical except for an additional 30 amino acids at the N-terminus of PPARG2. This results in a predominant adipocyte localisation for PPARG2, whilst PPARG1 is ubiquitously expressed. PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 1.0mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA)

app notes :

ELISA: Minimum Dilution: 1/8000; Maximum Dilution: 1/32000

other info1 :

Perservative Stabilisers: 0.01% Sodium Azide (NaN3)

other info2 :

Immunogen: Synthetic peptide corresponding to amino acids 255 - 268 of human PPAR gamma isoform 1. Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antisera to PPAR gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human

products description :

MBS221541 detects human peroxisome proliferator-activated receptor ? (PPARG), a member of the nuclear hormone receptor subfamily of transcription factors. Upon activation, PPARG forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARG is principally involved in the cellular assimilation of lipids, with key roles in adipocyte differentiation and adipogenesis. Two alternatively spliced isoforms of PPARG exist, termed PPARG1 and PPARG2, which are identical except for an additional 30 amino acids at the N-terminus of PPARG2. This results in a predominant adipocyte localisation for PPARG2, whilst PPARG1 is ubiquitously expressed. PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.

ncbi gi num :

116284368

ncbi acc num :

NP_005028.4

ncbi gb acc num :

NM_005037.5

uniprot acc num :

P37231

ncbi mol weight :

21,580 Da

ncbi pathways :

AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipogenesis Pathway 198832!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Developmental Biology Pathway 477129!!Energy Metabolism Pathway 198907!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Huntington's Disease Pathway 83100

ncbi summary :

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

size :

0.05 mg

price :

390 USD