catalog number :
MBS203038
products type :
Recombinant Protein
products full name :
Activator of Hsp90 ATPase-1 (AHA1, 19-337), Human, Recombinant, E Coli
products short name :
Activator of Hsp90 ATPase-1
products name syn :
AHA1; Activator of Hsp90 ATPase-1 (AHA1; 19-337); Activator of Hsp90 ATPase protein 1; Hsp90 co-chaperone AHA1; Activator of Hsp90 ATPase-1 Activator of 90 kDa heat shock protein ATPase homolog 1; Activator of heat shock 90kDa protein ATPase homolog 1; AHA 1; AHSA 1; AHSA1; C14orf3; HSPC322; p38.
other names :
activator of 90 kDa heat shock protein ATPase homolog 1; Activator of 90 kDa heat shock protein ATPase homolog 1; activator of 90 kDa heat shock protein ATPase homolog 1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); p38
products gene name :
AHA1
other gene names :
AHSA1; AHSA1; p38; AHA1; C14orf3; C14orf3; AHA1
uniprot entry name :
AHSA1_HUMAN
sequence :
MATNVNNWHW TERDASNWST DKLKTLFLAV QVQNEEGKCE VTEVSKLDGE ASINNRKGKL IFFYEWSVKL NWTGTSKSGV QYKGHVEIPN LSDENSVDEV EISVSLAKDE PDTNLVALMK EEGVKLLREA MGIYISTLKT EFTQGMILPT MNGESVDPVG QPALKTEERK AKPAPSKTQA RPVGVKIPTC KITLKETFLT SPEELYRVFT TQELVQAFTH APATLEADRG GKFHMVDGNV SGEFTDLVPE KHIVMKWRFK SWPEGHFATI TLTFIDKNGE TELCMEGRGI PAPEEERTRQ GWQRYYFEGI KQTFGYGARL
purity :
> 95% by SDS - PAGE
form :
Liquid. 20mM Tris pH 8.0, 2mM EDTA
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Heat Shock Proteins
products description :
The co-chaperone Aha1 (Activator of HSP90 ATPase-1) binds the middle domain of Hsp90(amino acid 272-627) and is proposed to function as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding. Recombinant Aha1 was expressed in E. coli and purified by using conventional chromatography techniques.
products references :
Meyer P., et al (2004). EMBO 23(6): 1402-10. Siligardi G., et al (2004). J Biol Chem. 270(50): 51989-98.
ncbi gb acc num :
NM_012111.2
ncbi mol weight :
36.1 kDa (320 aa), confirmed by MALDI-TOF.