14-3-3 gamma antibody (clone J3H10) | MyBioSource MBS200107 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

14-3-3 gamma antibody (clone J3H10)

catalog :

MBS200107

quantity :

0.05 ml

price :

240 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

product information

catalog number :

MBS200107

products type :

Antibody

products full name :

14-3-3 gamma antibody (clone J3H10)

products short name :

14-3-3 gamma

products name syn :

YWHAG; 14-3-3 gamma; Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; gamma polypeptide; Tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein; gamma polypeptide 14 3 3 protein gamma; 14 3 3 protein gamma subtype; 14 3 3gamma; 3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide; KCIP 1; KCIP1; Protein kinase C inhibitor protein 1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide.

other names :

14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 gamma; KCIP-1; protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; Protein kinase C inhibitor protein 1; KCIP-1

products gene name :

14-3-3 gamma

other gene names :

YWHAG; YWHAG; PPP1R170; 14-3-3GAMMA; KCIP-1

uniprot entry name :

1433G_HUMAN

clonality :

Monoclonal

isotype :

IgG2b, k

clone :

J3H10

host :

Mouse

reactivity :

Human, Mouse

sequence length :

247

purity :

By protein-G affinity chromatography

form :

Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

concentration :

1mg/ml

storage stability :

Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

tested application :

ELISA (EIA), Western Blot (WB) (Cell lysate)

app notes :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~2,000. Recommended starting dilution is 1:1,000.

other info1 :

Antigen Species: Human. Clone: Anti-human 14-3-3 gamma mAb, clone J3H10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-3 gamma protein. Immunogen: Recombinant human 14-3-3 gamma (1-247aa) purified from E Coli

products categories :

Signal Transduction

products description :

The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms,beta, gamma,epsilon, sigma, zeta, tau andtau that have been identified in mammals. The 14-3-3 gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

products references :

Chen XQ, et al. (2005) Glia. 42(4):315-24 Chen XQ, Yu AC, et al. (2002) J Biochem. 23;296(3):657-63

ncbi gi num :

21464101

ncbi acc num :

NP_036611

ncbi gb acc num :

NM_012479.3

ncbi mol weight :

28,303 Da

ncbi pathways :

Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Anchoring Of The Basal Body To The Plasma Membrane Pathway 1127503!!Apoptosis Pathway 105648!!Assembly Of The Primary Cilium Pathway 1127502!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054

ncbi summary :

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

size :

0.05 ml

price :

240 USD