product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
CKII alpha Polyclonal Antibody
catalog :
MBS194198
quantity :
0.1 mg
price :
440 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS194198
products type :
Antibody
products full name :
CKII alpha Polyclonal Antibody
products short name :
CKII alpha
products name syn :
CKII alpha; CKII alpha
other names :
casein kinase II subunit alpha isoform b; Casein kinase II subunit alpha; casein kinase II subunit alpha; CK II alpha; OTTHUMP00000029925; OTTHUMP00000029926; protein kinase CK2; CK2 catalytic subunit alpha; casein kinase II alpha 1 subunit; casein kinase 2, alpha 1 polypeptide; N/A
other gene names :
CSNK2A1; CSNK2A1; CKII; CK2A1; CK2A1
uniprot entry name :
CSK21_HUMAN
clonality :
Polyclonal
host :
Rabbit
specificity :
CKII alpha [Rabbit polyclonal antibody to CKII alpha]. This antibody reacts with human. Other species have not been tested. Antibody is affinity purified.
form :
100 ug IgG in 0.1 ml Triscitrate/phosphate, pH 7-8
storage stability :
Store at 2 - 8 degree C. Antibody is stable at 2 - 8 degree C for 1 year.
tested application :
Western Blot, Immunoprecipitation
app notes :
Western Blot: 0.3 - 1 ug/ml. Immunoprecipitation: Use Catalog Number 13030.
other info1 :
Antigen: Synthetic peptide representing a portion of the protein located within exons 12 and 13 (LocusLink ID 1457).
other info2 :
Stabilizer: None. Preservatives: 0.1% Sodium Azide
products categories :
Enzyme and Enzyme Inhibitor Antibodies
ncbi gi num :
29570793
ncbi acc num :
NP_808228.1
ncbi gb acc num :
NM_177560.2
uniprot acc num :
P68400
ncbi mol weight :
45,144 Da
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Alpha-synuclein Signaling Pathway 137913!!Axon Guidance Pathway 105688!!BCR Signaling Pathway 138058!!L1CAM Interactions Pathway 161003!!Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway 137984!!Measles Pathway 213306!!Measles Pathway 213277!!PDGFR-alpha Signaling Pathway 138049
ncbi summary :
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq]
uniprot summary :
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation. Ref.9. Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Subunit structure: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Interacts with RNPS1. Ref.9 Ref.10 Ref.11 Ref.16. Sequence similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.Contains 1 protein kinase domain.
size :
0.1 mg
price :
440 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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