This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Heme Oxygenase 1 Monoclonal Antibody
catalog :
MBS190201
quantity :
0.1 mg
price :
470 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GTS-1
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
catalog number :
MBS190201
products type :
Antibody
products full name :
Heme Oxygenase 1 Monoclonal Antibody
products short name :
Heme Oxygenase-1
products name syn :
Heme Oxygenase-1
other names :
heme oxygenase-1; Heme oxygenase 1; heme oxygenase 1; OTTHUMP00000198812; heat shock protein, 32-kD; heme oxygenase (decycling) 1
other gene names :
HMOX1; HMOX1; HO-1; HSP32; bK286B10; HO; HO1
uniprot entry name :
HMOX1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
GTS-1
host :
Mouse
sequence length :
288
specificity :
Heme Oxygenase-1 [Mouse monoclonal antibody to Heme Oxygenase-1]. This antibody reacts with human, rat and mouse heme oxygenase 1. It does not react with rabbit heme oxygenase I or heme oxygenase 2. This antibody will inhibit the activity of human or rat heme oxygenase 1.
form :
100 ug IgG in 10 mM PBS, pH 7.4, lyophilized.
storage stability :
Lyophilized antibody is stable at 4 degree C for 2 years. Store the reconstituted solution in aliquots at -20 degree C or at 4 degree C for 6 months after the addition of 0.1% sodium azide by the user.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
ELISA: 1:10,000 dilution with solid phase antigen. Western Blot: 5-10 ug/ml. Immunohistochemistry: 5-10 ug/ml (for use on human frozen or paraffin embedded tissue). Heme oxygenase 1 activity assays.
other info1 :
Antigen: Rat heme oxygenase 1.
other info2 :
Stabilizer: 1% BSA. Preservatives: None. Dilutions Instructions: Reconstitute in distilled water to the final desired concentration.
products categories :
Enzyme and Enzyme Inhibitor Antibodies
ncbi gi num :
579973
ncbi acc num :
CAA32886.1
uniprot acc num :
P09601
ncbi mol weight :
32,819 Da
ncbi pathways :
HIF-1-alpha Transcription Factor Network Pathway 138045!!Heme Degradation Pathway 160971!!Iron Uptake And Transport Pathway 187191!!Keap1-Nrf2 Pathway 198777!!Metabolism Of Porphyrins Pathway 106325!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Oxidative Stress Pathway 198916!!Porphyrin And Chlorophyll Metabolism Pathway 83021!!Porphyrin And Chlorophyll Metabolism Pathway 407
ncbi summary :
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq]
uniprot summary :
Function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Catalytic activity: Heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O. Subcellular location: Microsome. Endoplasmic reticulum. Induction: Heme oxygenase 1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. Sequence similarities: Belongs to the heme oxygenase family.
size :
0.1 mg
price :
470 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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