Recombinant Human Actin Gamma 1 | MyBioSource MBS142932 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Actin Gamma 1

catalog :

MBS142932

quantity :

0.002 mg

price :

140 USD

product information

catalog number :

MBS142932

products type :

Recombinant Protein

products full name :

Recombinant Human Actin Gamma 1

products short name :

Actin Gamma 1

products name syn :

ACTG1 Human; Actin Gamma 1 Human Recombinant; Actin cytoplasmic 2; Gamma-actin; ACTG1; ACTG; ACT; DFNA20; DFNA26; Actin Gamma 1

other names :

actin, cytoplasmic 2; Actin, cytoplasmic 2; actin, cytoplasmic 2; cytoskeletal gamma-actin; epididymis luminal protein 176; actin gamma 1; Gamma-actinActin, cytoplasmic 2, N-terminally processed

products gene name :

ACTG1

other gene names :

ACTG1; ACTG1; ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176; ACTG

uniprot entry name :

ACTG_HUMAN

host :

E Coli

sequence length :

375

purity :

Greater than 95.0% as determined by SDS-PAGE.

form :

Actin Gamma 1 at a concentration of 2 mg/ml in 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3. Sterile Filtered clear solution.

storage stability :

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Actin

products description :

Description: Actin Gamma 1 Human Recombinant produced in E Coli is a non-glycosylated, polypeptide chain containing amino acids (1-375) and having a total molecular mass of 41.8 kda. ACTG1 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques. Introduction: Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells.

ncbi gi num :

316659409

ncbi acc num :

NP_001186883.1

ncbi gb acc num :

NM_001199954.1

uniprot acc num :

P63261

ncbi mol weight :

41,793 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Axon Guidance Pathway (105688); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Developmental Biology Pathway (477129); Dilated Cardiomyopathy Pathway (121494)

ncbi summary :

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]

uniprot summary :

ACTG1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Protein type: Cytoskeletal; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: filamentous actin; extracellular space; cytoskeleton; myofibril; membrane; plasma membrane; nucleus; cytosol. Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding; ATP binding. Biological Process: axon guidance; retinal homeostasis; intercellular junction assembly and maintenance; ephrin receptor signaling pathway; innate immune response; sarcomere organization; vascular endothelial growth factor receptor signaling pathway; cell motility. Disease: Baraitser-winter Syndrome 2; Deafness, Autosomal Dominant 20

size1 :

0.002 mg

price1 :

140 USD

size2 :

0.01 mg

price2 :

205

size3 :

1 mg

price3 :

6000