product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Peroxisome Proliferator Activated Receptor Gamma (1-477)
catalog :
MBS142828
quantity :
0.01 mg
price :
610 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142828
products type :
Recombinant Protein
products full name :
Recombinant Human Peroxisome Proliferator Activated Receptor Gamma (1-477)
products short name :
Peroxisome Proliferator Activated Receptor Gamma
products name syn :
PPARG Human 1-477 a.a.; Peroxisome Proliferator Activated Receptor Gamma Human Recombinant; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; PPARG; NR1C3; PPARG1; PPARG2; PPARG (1-477)
other names :
peroxisome proliferator-activated receptor gamma isoform 1; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma; PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3
products gene name :
PPARG
other gene names :
PPARG; PPARG; GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; NR1C3; PPAR-gamma
uniprot entry name :
PPARG_HUMAN
host :
E Coli
sequence length :
477
form :
PPARG at 0.1mg/ml in 50mM Tris-HCl and 10mM L-glutathione (reduced). Sterile Filtered clear solution.
storage stability :
Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months. Avoid multiple freeze-thaw cycles.
tested application :
ELISA (EIA), Inhibition Assays, Western Blot (WB)
products categories :
PROTEIN KINASES; Enzymes; Peroxisome Proliferator Activated Receptor
products description :
Description: PPARG Human Recombinant encoding amino acids 1-477 expressed in E Coli, is fused to a GST tag and it is antibody reactive.The PPARG is purified by proprietary chromatographic techniques. Introduction: Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferators activated receptors (PPARs). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids.
ncbi gi num :
116284368
ncbi acc num :
NP_005028.4
ncbi gb acc num :
NM_005037.5
uniprot acc num :
P37231
ncbi mol weight :
21,580 Da
ncbi pathways :
AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipogenesis Pathway 198832!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Developmental Biology Pathway 477129!!Energy Metabolism Pathway 198907!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Huntington's Disease Pathway 83100
ncbi summary :
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
size :
0.01 mg
price :
610 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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