product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interleukin-1 beta, His Tag
catalog :
MBS142356
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142356
products type :
Recombinant Protein
products full name :
Recombinant Human Interleukin-1 beta, His Tag
products short name :
Interleukin-1 beta
products name syn :
IL 1 beta Human, His; Interleukin-1 beta Human Recombinant, His Tag; Catabolin; Lymphocyte-activating factor (LAF); Endogenous Pyrogen (EP); Leukocyte Endogenous Mediator (LEM); Mononuclear Cell Factor (MCF); IL1F2; IL-1 beta; IL 1 beta His
other names :
interleukin-1 beta proprotein; Interleukin-1 beta; interleukin-1 beta; IL-1 beta; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta; interleukin 1, beta; Catabolin
products gene name :
IL 1 beta
other gene names :
IL1B; IL1B; IL-1; IL1F2; IL1-BETA; IL1F2; IL-1 beta
uniprot entry name :
IL1B_HUMAN
host :
E Coli
sequence length :
269
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
IL-1b His is supplied in 1x PBS and 50% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-1 beta His-Tag Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 153 amino acids fragment (117-269) and having a total molecular mass of 21.88 kDa fused with an amino-terminal hexahistidine tag. The IL-1b His is purified by proprietary chromatographic techniques. Introduction: Interleukin-1b is a potent pro-inflammatory cytokine produced by a wide variety of cell types including monocytes and macrophages. It displays a broad range of biological activity including activation of B and T cells in response to inflammation and the activation of endothelial cells.
ncbi gi num :
10835145
ncbi acc num :
NP_000567.1
ncbi gb acc num :
NM_000576.2
uniprot acc num :
P01584
ncbi mol weight :
30,748 Da
ncbi pathways :
African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Cellular Roles Of Anthrax Toxin Pathway 138076
ncbi summary :
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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