product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti-GSTP1 Monoclonal Antibody
catalog :
MBS130154
quantity :
0.04 mg
price :
150 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
ELISA, immunohistochemistry, western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS130154
products type :
Antibody
products full name :
Mouse Anti-GSTP1 Monoclonal Antibody
products short name :
GSTP1
other names :
glutathione transferase [Homo sapiens]; Glutathione S-transferase P; glutathione transferase; glutathione S-transferase pi; EC 2.5.1.18; GST class-pi; GSTP1-1
products gene name :
GSTP1
other gene names :
GSTP1; GSTP1; PI; DFN7; GST3; FAEES3; FAEES3; GST3
uniprot entry name :
GSTP1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
host :
Mouse
sequence length :
210
specificity :
Full length recombinant protein (WB). human GSTP1 recombinant protein (ELISA). Human prostate tissue (IHC)
purity :
Mouse Anti-GSTP1 is purified by protein A affinity chromatography.
concentration :
1 mg/ml in 10 mM PBS (pH 7.6). 0.02% sodium azide and 10% glycerol
storage stability :
This product remains stable for one to two weeks if stored at 2 degree C to 8 degree C. For long-term storage. aliquot and store at -20 degree C or below. Use before is one year from the date of receipt.
tested application :
ELISA, Immunohistochemistry, Western Blot
app notes :
Western Blot: 1:500-1:2,000. IHC(P): 1:500-1:2,000. IHC(F): 1:500-1:2,000. ELISA: Propose dilution 1:10,000. Determinining optimal working dilutions by titration test
other info1 :
Immunogen: Ni-NTA purified truncated recombinant GSTP1 expressed in E. coli strain BL21 (DE3). Antigen Species: Human
products categories :
Cancer/Apoptosis Pathway
products description :
GSTP1 (glutathione-S-transferase. pi 1). also called GST3/DFN7. which is located on chromosome 11q13. is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene. which when inactivated leads to tumor growth. and the class glutathione-S-transferase is commonly inactivated by somatic CpG island hypermethylation in cancers of the prostate. liver. and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (
products references :
Kimihiko Satoh. Ken Itoh. Masayuki Yamamoto. 2002. Carcinogenesis. 23: 457 - 462. Xiaohui Lin.William G. Nelson.2003.Cancer Research. 63: 498-504.
ncbi summary :
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
uniprot summary :
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalytic Activity: RX + glutathione = HX + R-S-glutathione. Subunit: Homodimer. Interaction: Q99683 ; IntAct= EBI-353467,EBI-476263 . Interaction: Q16539 ; IntAct= EBI-353467,EBI-73946 . Interaction: Q12933 ; IntAct= EBI-353467,EBI-355744 . Similarity: Belongs to the GST superfamily. Pi family. Similarity: Contains 1 GST C-terminal domain. Similarity: Contains 1 GST N-terminal domain. Web Resource: Name=SHMPD; Note=The Singapore human mutation and polymorphism database; URL="http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=GSTP1";.
size :
0.04 mg
price :
150 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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