This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GPX4 / MCSP Antibody (C-Terminus) LS-C56834
catalog :
LS-C56834
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA
product information
AntibodyID :
57304
AntibodyName :
LS-C56834
TargetSpecies :
Mouse
Host Species :
Rabbit
Product Name :
GPX4 / MCSP Antibody (C-Terminus) LS-C56834
Specificity :
Detects a specific epitope within the carboxy-terminal of mouse glutathione peroxidase 4 (GPx4) also known as phospholipid hydroperoxidase (PHGPx). GPx4 is a 20-22kD selenoprotein that has an important role in preventing lipid peroxidation, and is thought to protect biomembranes against oxidative stress. GPx4 is expressed in high levels in testes, suggesting a role in male fertility. It has also been identified as an enzymatically inactive structural protein of the mitochondrial capsule of sperm. GPx4 has also been proposed as a modulator of various eicosanoids, which serve as inflammatory lipid signalling molecules.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, pH 7.2, 0.01% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to amino acids near the C-Terminus of mouse glutathione peroxidase 4.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Short term: -20°C; Long term: -20°C.
Gene :
GPX4 / MCSP
StandardGeneSymbol :
GPX4
Reactivity :
Mouse
Usage :
ELISA (1:7000 - 1:30000), WB (1:500 - 1:3000)
ShortWebDescription :
MCSP antibody LS-C56834 is an unconjugated rabbit polyclonal antibody to mouse MCSP (GPX4 ). Validated for ELISA and WB.
UsageText :
Western Blot: LS-C56834 detects a band of approximately 19kD in mouse testis cell lysates.
Synonyms :
GPX4, GPx-4, MCSP, SnPHGPx, Phospholipid hydroperoxidase, SnGPx, Glutathione peroxidase 4, GSHPx-4, PHGPx
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.